Oops. That's the word that comes to mind when reading Michael Carroll's thoroughly nerve-wracking book, Lab 257: The Disturbing Story of the Government's Secret Germ Laboratory" ... about the federal germ facility on Plum Island. The island [is] home to some of the deadliest microbes festering on the planet. According to Carroll's book, the island -- and laboratory -- are also home to slipshod construction, poor safeguards, and lax security. "Lab 257" claims errors at the facility caused Lyme disease outbreaks and health problems for the local population -- claims disputed by the U.S. Department of Agriculture, which ran the facility until recently. Carroll [said] that the point of the book was to expose the potential hazards of a poorly run institution; he has nothing against better-run, more secure institutions. "You have to know how things interact, germs, bacteria, etc. You [just] don't need to create millions of them to know how to create them and make them more virulent. Like other government scientific facilities, it's had an aura of mystery: Plum Island earns a mention in "The Silence of the Lambs," and thriller writer Nelson DeMille set a novel there. Much of Carroll's research was done through interviews with nearby residents, as well as documents and reports. While the government was "cooperative at the outset," Carroll said ... he was later denied access to the facility. Carroll isn't the first to offer criticism. In 2002, after a power outage on the island, New York's WABC-TV did a story on whether containment procedures worked; several employees questioned the lab's safety. In 2003, the General Accounting Office listed security problems on the island, partially prompted by a whistleblower, Jim McCoy, who protested the management of a private concern.