Did you ever feel your own shoulders relax when you saw a friend receive a shoulder massage? For those of you who said "yes," congratulations, your brain is using its power to create a "placebo effect." For those who said "no," you're not alone, but thankfully, the brain is trainable. Since the 1800s, the word placebo has been used to refer to a fake treatment, meaning one that does not contain any active, physical substance. Today, placebos play a crucial role in medical studies in which some participants are given the treatment containing the active ingredients of the medicine, and others are given a placebo. These types of studies help tell researchers which medicines are effective, and how effective they are. Surprisingly, however, in some areas of medicine, placebos themselves provide patients with clinical improvement. Research suggests that the placebo effect is caused by positive expectations, the provider-patient relationship and the rituals around receiving medical care. Depression, pain, fatigue, allergies, irritable bowel syndrome, Parkinson's disease and even osteoarthritis of the knee are just a few of the conditions that respond positively to placebos. In addition to the ever-increasing body of evidence surrounding their effectiveness, placebos offer multiple benefits. They have no side effects. They are cheap. They are not addictive. They provide hope when there might not be a specific chemically active treatment available. They mobilize a person's own ability to heal through multiple pathways.