A friendly smile. A food pantry donation. Such acts of kindness have a self-serving upside ... as science has conclusively shown they also make you healthier. UCLA is poised to advance that science with the ... launch of the world's first interdisciplinary research institute on kindness, which will explore, for instance, how and why being nice to others reduces depression and the risk of cancer and cardiovascular disease. Research by UCLA scientists already has shown that mindfulness and kindness actually alter the behavior of genes, turning down those that promote inflammation, which can lead to heart disease or certain cancers, and turning up the activity of genes that protect against infections. But the ultimate goal of the UCLA Bedari Kindness Institute is to spread kindness and promote a more humane world. It will develop training tools to help practice kindness and spread them through online programs, public lectures, media outreach and a free app called UCLA Mindful. When it comes to kindness, the intention, rather than the outcome, is key. In other words, it's the thought that counts, as the adage goes. "Cultivating kind thoughts increases the frequency of kind actions, and both the thoughts and the experience of engaging in the actions have positive effects on the well-being of the individual," said Daniel Fessler ... the institute's inaugural director. The institute's work ... will focus on three themes: the roots of kindness, how to promote it, and how to use it as a therapeutic intervention to improve mental and physical health.