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Researchers say new blood test can spot more than 50 types of cancer — many hard to detect early
Key Excerpts from Article on Website of CBS News


CBS News, November 3, 2021
Posted: November 21st, 2021
https://www.cbsnews.com/news/cancer-blood-test-early-detecti...

The sooner most cancers are discovered, the better the odds they can be successfully treated. Mayo Clinic participated in research on a test that can detect more than 50 cancers. "My dad, he was a healthy guy. He didn't have any known risk factors for cancer," Dr. Julia Feygin said. Feygin lost her 40-year-old father to pancreatic cancer when she was 13. Diagnosed at stage three, he lived for nine more months. "I strongly believe that purpose can be found in everything that happens," Feygin said. She's now part of a team at a Menlo Park, California-based company called GRAIL that's introducing the blood test, called Galleri. She says can it catch hard-to-detect, aggressive and often deadly cancers like pancreatic, ovarian and esophageal. "If cancers can be detected early, we can dramatically improve patient outcomes," Feygin said. Feygin explains that our blood contains a DNA signature. The blood test tracks the DNA a cancer cell sheds. Two tubes of blood are drawn and sent to GRAIL's lab for analysis. "We can find and sequence these tiny bits of tumor-derived DNA in the blood and, based on the patterns we see, we can reveal if there is a signal for cancer present. We can predict with very high accuracy where in the body this cancer signal is coming from," Feygin said. An interventional study that included Mayo Clinic with 6,600 participants returned 29 signals that were followed by a cancer diagnosis. Another study found a less than 1% false positive rate.

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