Submit an copy Sub,@it an a@4diti*-al TRAVEL VOUCVIER ttto originating offic's desires &n suditvd copy GI thl. 2 returned. NAM OFFXCIAL DUTY $TATCf4 3031 PERIOD CO2VERED BY THIS VOUCHER TRAVEL ORUER MUNIIYER 5 Docembe@.- 1955 TSS SUMMARY OF EXP'--NSES CLAIMED BY TRAVELER T441S SPACE FOR FINA14CE USE ONty _!ILFI LI I 2 s VOUCHER No. TRANSKJ((TATION OTHER I OTAL cLk" A ED ?i ES AND TICKETS FURNISICED2 LESS ADJIJSI ICENTS.. -AUOs SALA4CE DUE 'CRAVELER EXCES. ADVANCED TO BE REFUNDED '1-?. 41 (Atta.h C-PY -f el-nd PAYMEriT INSTRUCTIONS, CERTIFICATIONS AND APPIOVAL i certify that this voucher oitd any ottachirentl arf CorreCt, the ex- pense.s were in4ciirted on off-c;*i business of a co;fident;ol n '- re, 2 NET APPROVED 5 otu paymeit or cied;t has i-at &ten received; all quartes or meats for- CREDIT TO ADVANCE nished without charge are seated with oppropr;ote dt2duct,'On from ACCOUXT' $ per diem; and any leave token has been noted in the ifirtrary,.- DATE S rNATUFtE OF PAYEE NET TO PAYEE i@' 2 TRAVELER NOIIFIED 4 1956 THIS BALAI%NE DUE APPROVED CERrIFIE0 FOR PAYMENT OR CREDIT 2 DATE SIGNATURE Of APPROVING OFFICER DATE AUTHORIZED C RTIFY-,N-. O@@CR l CERTIFY FUNDS ARtYVZft7;@a-LY"" OLIGAT!Oti REFERENCE i4O. -TC;@k@,aE ALLOTME14T r*, DATE S2IGNATKJRE OF AUTHORIZING OFFICER SPACE BELOW FOR FINANCE USE ONLY (13-22) (C-42) (47-Y) (53-57) "59-67) .70) (71 -M) 2 GEN--RAL OBJEC. DESCRt?'riOt4 EXPEND ADVANCE ALLOTMETAT LED@,Elt AC14:T. W-3. live AMOUNT CODE ACCT. MI). L[DRER 2 ACCT.NO. CLASS X ti3LICHFR NO. bEci7 lop%k k" 22 II",F PRLVIOtl!; tOtll.3N OF Illig ft)Rtt@ RtPLA(tS FORM 33-?2 WHICH 15 OC',OLETE 'C--a 13 'rilly D@',l t* r-o e 0 t ran-du l@@ 5 ob-,@rze4 to r,.I-Iot- Va-3 1: "i r 1956) LIT ON - IVI@@,:14 ism oz t,-c- 4'75 wanua;y@ 7 18,475 .4:r-k?09.4 FCR: TFIE RECCRD KKULTRA Subproject 54 SU,3JECT' 2 work on the The purpose of @@ject 51@-is to contiiiua r,,oaht@nt" of brain coneus Yir has recently completed a prelj_mtnary study tinder- contract. 2. _The scope of tne resA,.,arc'h Pro2gram will be to pursue stti4,ies fluid on the resoiancc--cavitatio,@i tl@eory of brain concussion using a filled glass ei,-.-,ilated skull. t' th^,above, extensive 2 Ta eaditio,-i o peri, -- rrld(i qat for poasible correla- cadaver imp@let ex meats will 'be ea -- f the with the above tboory@@-7For-a mo.-o detailed e3,Tl,anp-tio2n o ecopo of the progra-% soo-the attached proposal. 3. The-cost of this-PrOgrm is ostimAt,.-,d to be vk6OlOOO f or a peri.,A of One Y03-r startirig 1 Febra&ry-1956i To this -= must be $2.,400-2reprosenting a lour petd6ht tervico charge to the---- Therefore, tha total-cost will not exceed @t6?.,400. '7',qa-aij's--Bhould be m-ade ag ainev Allotmont 6-2502-10-001.-- t;, t3 2 has reqtiestecl the 4-,. The to -.ub-,dt to it a s ting of inonios ree6ivi-d from- 5. Upon torairtion of the project or withdrawal of finc%-qctal Support by tho sponsor, disposal of Pe t eoui2lpL.Ment Shall follow rm@uien the sche-l-ale (Para, a-o) under "Proposed Budget"; set forva in the atvohod proposa-L. 6. Tt was rutually agrec-d that docii.;e-@itation Prd aecot2inting for t nses--wbich are-reimbw-sablo-by t$ie shall---c-o,-nform with the accepted practicbd of that corporationi 7. @@r. ANDSWoread to - -oply with the roquir 2 co-L emonts of the -a of Agreemen Memorar,?Atb o@n cal Division APM. OVID FCR OBLIGATIOII OF FLIIDS: APFRCVED: ReregLreli Director em cal Division DaLto. iliopos.%l Dis'lri.bution: OrteLin-I Only Amok TRANSMITTAL SLIP A 3 Room 1441). poo,@i No. EXTENSION Fe cq "O' 3 6- 8 PROPOSAL 16 December 1955 sUBJE(,'T-. Requpst for Suoport of Research on the Mechanism of Brain Concu.-,sion 1. This is a request for financial support foi- research on the rqechanism of brai.n-6ohdussion for the period I Feb 1956 to I Feb 1957. -2. The re3onance-c-avitation theoiy upon which this research is to be bas2e has been presented in the proposal-sut)niitted to th Nm-Eell - dated 27 liarc-h 1954. 3@ The progrpjn as originally sut)-itiitted estijiated the-duration of the program to be from three to five years requesting a total of $72,109 for the initial year. 4. At the request of the 2 a reduced bxiiget was submitted. ig 5. unting to $24,925, was then awarded to the to support this pto_aram from I Feb 1955 6. The progress made to date urit3or the above contract can be s'L)lmn-ai@ized as f oll.'ows A. RESFK-RCH FkCILITIF.'7i The following research facilities have been established for the investiaatiozi of the very diverse aspects of the problems being stu,,3iei. a Atota',L jf--@5-06'7q:aare feet of I.aborato' and office space 2 LY eq@dpped with much of the diversified machinery and apparatus necessary for research in this field. b. Blast Range at located A blast range has been established 2 a pri rliximately -no - e M'W f th ,inwrr'@60@ia O@l.-Y. This C) area is owtic@1-1 by -losed to the public. Tbree blast test-5eries have been ran to date. Ari,@ingitiorits have been made with the for use of their human cadavers. A- test ,tre.,A his been assigned for this WAkr@['4(NG s LLIGV-NCE Af,4D METHOL)S iNVOI@VEt) specific work. impact tests have been conducted on trro,9 cadavers to date. This work is beina. conducted xuider the direction c,- TEL Both full-titte technical perso-r@n(-,! part-time professional research personnel h2ave been acq@Aired and inkiootrinated relative to their specific function. C.- TECHN'ICIXL PROC@RFSS Folloitling is the technical-prg,,Yress made under the cui-rent contract: a. Specialized instrmentation and niir2acrous testing -techniques have been developed to obtaia-.the desired dyiimiq data. b. Considerabl6 data has noii been obtained supporting the resonance-cavitation theoi'y-of-braiii concussion. c. Prelirin-nry a2cceleration threshold data has been obtainea for a fluid-filled glass suaiilated-skull. d. Dita has been obtained-on-the nature and the rqagnitii@le of pressure fluctuations within a glass strulated skull subject to either impact or sound waves propaaated in air 2 e. TLiitial studies have been made on the simulated glass skull atter@ioting to establish the eavtation-patterns for various types of impact. The proposed method and proaram plan reraain the same as stated in the 11 oricin2.,ql prc@pogal, except for the temporary deletion of the -bqmcrsion 0 - blast study. 8. The current level of activity on this project can be indicated I)y the ow 0--th -November, which amowit most recent bil'lin,- to thel@ f r e month of c-d to $4,034.61. 9. In the interest of efficiency and econonq it is reqiiested that at least this level of activity be maintained for the coriiiia year. WARNING- N r--T@iOD'S INIVOLVC.!) % 1 0. 0 PCrTEIri YAL APPLICATIONS Ob- TH,E RECMCH FTNDIIIGS 10.1 Trotter, W. def ir-,e3 brain concussion as: "an essentially ti,ansient state due to head injui-y which is of instantanious 2 bhs6t, manifests widespread syinptgir@s of @)iirely paralytic kind, does not as such coiyfprise any evidence of strue'.ural e cerebial injury, and ' al4aysfoll d by affiries @k for th 6etu4l mom2ent of the accident." 10.2 The-iraplication of the underlined portion of the above statement is that if a technique were devised to induce brain concussion without givina_ either advance wa-rnina or causing external physical trauma, the person upon recovei-y would be unable to recall what had hplipen2ed to him. -Under these conditions the s;krne technique of produoiri,- the concussion could be re-used ri-qrq times without disclosure of its i-,ature. 10.3 First, considering the possibilities of direct impact to the head.cr.-body, it should-bp-Tpossible2fi,oni-the--j4'indings of this research program to determine the following: a. Qptigitim design of -iriliactizig devices. b. Optimi-ua points of i.,ripact on sloill or body for the specific effects desired. 2 c. Tnterisity-o.L@ the blow-for the e--'fect desii,ed. i 10.4 In re8"ax-d to the potential-impacting devices, there are certain design reqiisites that are apparent at-this tire: a. The impact should be dolivered'withoiit 2 advance warning. b. The area of impact ani force distribution should be such that surface tra-an-a does not occur. c. The intensity Of the iTripa@.-ting force and its duration should be such as to obtain 2 the desired effect. d. The device should be as small and as silent as possible. 10.5 The specific impactin..7 devices right take the foi@iti of any of the f ol,lowinc - a k pancake type black-jack givin2-, a high peak impact force with a low unit surface pressure. b. Concealed or camoufl-agod sprino@-loaded iiipacting devices that ti@igper upon contact with the head. (ori-inal -ttid sole copy --WARNIN 8 E SFN@ l@',4TELt-IGL@@C-E ',')u4W'; '-'@ETliOL)S li'i%'OLVEU nacter such as an air gun 0. A projectile type im, using A small shot filled sack for a projectile. d. An explosive pad detonated in contact with the head or the body. 10.6 Let us now cotisider the possibilities of e-Kcitino the resonance cavitation directly without impact. There is considerable evidence that resonance cavitation can be indiaced directly in the following Ways: a. A blast wave propagated in air. (Blast Concussion) b. ihysical excitation with a mechanical driver 2 o! hoi-ii, ti-med to the resonant frequency of the hea wave-propa-ated in air rqtist have considerable 10.7 A singlc blast pressure 0 intensity in order to produce brain concussion, however, there i3 considerable evidence (Cai-ver & Dinsley),that modification of the pressure wave can produce profound effect--. 10.8 Excitation of the resonance cavitation by usino. a tuned dr-Lver at -this tirie appears to be well within the relm of possibility. The neurotic-lik-- FLanifestations noriiially associated with blast 2 concussion could possibly be induced by this niethod. Use of this me-thod,@ioAever, would require actual Vn.vsical contact with the drivers. 10.9 Excitation of the resonance cavitation by tuned sound waves also appears to be a reasonable possibility. Concentration of the sotirid- 2 field at some remote point could be effected with accou3tical lenses and reflectors. The blast duration would be in the oi@der of a tenth of a second. 1','Asking of a noise of this duration should not be too dificult. 11.0 It would possibly be advantageous t2o establish the effectivness of both of the above methods as a tool. in brain-wash therapy. A full knoiiled-e of the method and the resulti@ng sequela should be of aid to arq person forced to subrait -to such treatment. 12.0 Possibly tl,,e most significant potential aspect of this study would be in the de2velol)Lr@ent of practical ireans of aiving a person irm@.-iunity, even though teutporary, to brain concussion. C.'no techr' i-tque that appears to have potentialities involves the i.ntrodiiction of a small quantity of_gas, a-pproximately I 2cc, into the spinal cci-d. I'his gas bubble would then norral.ly inicrrate t,o the ventricles located'at the centi-wi of the-braii-t. The ability of t't'lis bubble to expand ui-i(ler dynamic t effect'Lve ill Dreventina resonance cavitation 8 loRdir@c,, would be v@os froia occuring. VW (Original and sol-e col)y :ag-?,) AN!) i'@, PROFOSED BLff)rFT (1 Feb 1956 to 1 Feb 1957) Direct Labor $23,59,@ Yiaterials 41000 Overhead (83-21% of $@3,594N 19,633 2 -vel Tr@, 800 Consultant Fees 1,000 laboratoi7 Equir-)ment** 10,000 r,ontingencies 973 2 Total -$6o,ooo See attach6d lettei@-for breakdown. In regard to the laboratory equiy)rqent the follo@i-.ng stipulations are propcsed: a. The laboratoz7-eqiiijvierit will be purchased by the contractor at the start of the years2 program, however, the sponsor will re.i,na.in legal owner of the equipi@qent. b. Ihe book value of the abQve-eqxLipiiient-wi'-l then be depreciated cver a five year period by the sum of the digits method. The schedule of depreciation will then be as f2ollows: st yen,' =-5/15-origiiial-cost Znd year = 4/15 it 11 3rd year = 3 15 it n 4th year = 2 15 11 5th year = 1 15 2 c. If at ariy time the sponsor @rit@idrai@is financial support, the contractor is then to be granted 1 year rentfi,ee use of the eqviit,mient. d. fit the end of this grace period the contractor has then the option of purchase from the sporisoi- of any or all items of 6qxiirifnent at the then deprec-i-@tted value. e. fi@t the end of the five years of life the individual items of equ-i,l)ment h-ave no book value and @iutom.,it4.-c@tll.y become the property of the7 coi,itractor. -qCt4SlTiVE ItITELLiGEN "'Uri'(,E!; ATID f,',CTliODC It' Y'ROPOSE@D SCHEDUE OF PAY@IENT 1 Feb 1956 $22,500 i may i956 12,500 i Aug 1956 12,500 I N,@,v 1956 12,500 Total-- ---$6o.000 4 ecto.@ of Research @IOTICE D@,-Cenber 16, 1955 At-ei-i-ion: Pucsuan"%-O to our t@-l-eplion-- co.-ivergation of.' 'D2cer,,bor 15, 1955J we hav- coi-,i)u--d the astir..,,a,@--ed-burdon rate applioable to 2your researeb con4vxacl--,-. fo.- tl)a fiscal .r--ar 8--pteiCoer ;-:)O., TAI-I ee,5tAre@ated overhead foi, the y--ar e-ijifitiFS Septer:oer 30, 19,s6j based udon tli-@% corporat@lloi,ls e-,i@oerience for t.be paiiod fro:,4 Juino 1, to '3ooteL-il-,43r so, 1955, cei@@ai7-1 actual a.%-oenae,-, for tlie r..ontli of-t-@'oveniber,-laj5.5, c,.ind ,c.).ddition-al c-stii-ia@ked e;tDet-,sas a3 furnish2ed by lir.11 Is coripri-.ed Utili tiea .3 C, 0 Sbop Su:.jplies and Exoense 1,500 Reproduction Costs 500 r-,'-,Paira and 360 D,--@preciation, Resoareb Equipire2nt 3,99G 06 Office Furniture - atid FL-ctures 324- OfL@icers' Calarieu, Adriiniutrative 1,933 @-iffice Salaries, Secre'u-arial A@..Oao 1'racati2o,,i Pay I , '--' 7 @O Payroll Taxes 1,02-1 A@-ioptir.'a-tion of L-,,,ischol-6. and 0 f ,': 1 C ai,-: @ s 420 W A F@ N I i'@4 t"0-" INTELLIGFNCE 0 Tixes., Licenze* -Lnd Perrii@s 1324 DLies and SubscrIT)tlon3 48 Aut-o-,,-obila Exooiise 600 2 Dr-,proci-ation, Autorq@tive--,-.-- 2qUip,7!e.-It 336 Froooo--al Costs 240 Otiie:l G-o@ie-.-al -@nd-2 Fr',o';:i;ilnistrative r,,xy)enses- Boo Total Estimted overheid Tine to4-al est,Lr,,,-'ed dir cc '%-, -labor - L'or 4%-Illo fiscal year------ v L' 2 - - - endin- Santer..-.h.--r 3o., is @31 459, based upon -Lie Drodt,,c,@-ive hours and the &,!c)n -0 -Tove.,ibar, The esti,,,iated bur@c-n-i-i r-at,32 is-ba,,ied uoon Ikli,. a ,,setir-ii)tion that the present pei,sonilal i-iiii conti-nue 'subat@ajitially-ti.,ici,,an@,r@ed ti.)roue.@ out the year* i-n--rease or decrease in-direct labor would affeelt-I the burcen 2r,,-to. The eatii,-i,3Lted overall biii@den rate, wliieh i-iould be allo- cable to all direel., labor cos@.-s, is E;3.fli De,@,cent, Qolrl.)u',,-cd by ezti.,ilated overheap@'-'-P--@';@'6,PI77 -by tb e ted o direct labor., 3 1, 5 9. The er>,ti@.at.-d cos'Ls for the endinl- ti v 1956, ozi2 gover,-ml--rt-.'.- co-qtracts bein,- vi,,-.:,ol-ial-ed ,-,t this ti,-re, based -1 11 v 11 on the ttial@L. 75 p--rc.-tit-of-the research will be on-thes con,@,2r,:@et3, are as follo7iis:-- Direct LaLor (75,;@-of-@31,-459) @i , 5 9114 i@@'iterials 4.,Ooo Burdc-,.i of-' Costs coi2atracts only: Travel 800 Conoulte@nt Peas 1,000 Co,itinrrencies 973 2 77.3 Total Cost of Goverqriont Co n'@-I ric t 3 9 Very truly yo"rs, WARNI 'TELLIGENCE NLETHODS INVOLVED S@Ltbnlit Of",4;n.1 nd VD c@,lpy Submit an seditional copr it TRAVEL VOUCHER 2 off,-. -a aud;ted copy of the vo,ch,, returned. NAME OF PAYEE. ORPICIAL DUTY STATiot4 2 T. 31 PE2RIOD COVERED BY THIS VOUCHER TRAVEL ORUCH NU ABER OR AUTHORITY FQR TRA-IIEI. FROM SUMMARY OF ERPENt5@ CLAiNiEri By TRAVELER 2 THIS SPACE FOR FINAriCE U,E ONLY PER DIEM 5 &Fk3. 00 VOUCHER t4o., TRANSPORTATION OTHER 2 TOTAL CLAIMED TOTAL S LESS ADVANCES AND TICKETS lift.@1110 LESS ADJUSTkiENTS: BALANCE DUE TRAVELER 2 r7 EXCESS ADVANCED TO BE REFUNOED (Attach copy of,efur-d r,-co@'pt) PAYMENT INSTRUCTIQ,%S- CERTIFICATIONS &ND 2 APPROVAL I certify that this voucher ard any attachments ore co"ect, the ex. AUDITED BY Penses were incuri;ed on official business of a conf;dtnti',it nc:turz, 2 NET APPROVED S POYment Of credit Ads not bitn received; all qvcrttfs Of RPCOIS fur. CREDIT TO ADVANCE nished w,'thout cborge are slooei with appropriate cleduct"on fton ACCOUNT'- per cti4m, and any leave taken La, been 'ot4ed in the itinerary. DATE ---JSIG.,AkTkURE (@F PAYEE 2 NET TO PAYEE TRAVELER NOTIFIED 2 THIS BALANCE DOE CERIIF@ED FOR PAYMENT OR CREDIT DATE PFWV@NG OFFKER DATE 2 AUTMORIZEO CERTTFYING OFFICER t CE'TTIFY FUNDS ARE AVAILABLE ;@OLIGATION REFERENCE NO. 7CHARSI--@LLOiNIENT NO, DATE -VSI@IIAT.F& OF AUT2HORIZING OFFICER SPACE BELOW FOR FINA,4CE USE ONLY (13-22) :40 42) (47-$2) (59@ 67) (F4-70) (71 -W) EXPEND, ADVA'ICE GENERAL ALLOTMENT LEI)GER ACCT. NO. OBJEC. DESCRIPTION CODE AECT. NO. LW.CR TIVE 2 A40UNT ACCT.NO. CLASS x W"C)irR No. otait CREDIT 6 11 R. It-'!E PRCV!OT;S (OIIIQN Or TiliS FOf@Nt@ 22 RLPLACLS FORM 33-14 W@i-C" IS Ob'OLETE@ SECRET FUNDS AND TRAtiSPORTATION TICKETS AL)VANCED TO TRAVELER DATE AMOUNT -DF RATE TO U@ S. S AMOUNT SOURCE F'ORK:IGN CURRK:XCV U. S. I TOT At -.4*W II v'.# TRANSPORTAT.10N A@'40 EXCHANGE ORDERS. BOTH USED AND NOT USED (Attach &Qe;pts. stubs. and unused its@m@s) INCLPJSIVE D MCA-. Cf TRAVEL' POINTS OF I'K&YEL -COST ATES FRCK TO Z. . 2 J-@ TI Gf3CtViC*'L@$CJ, etC. SCHEDULE OF EXPENSCS A.NO ITIIERARY OF TRAVEL---R DATE 2 DESCRiPTIONGFEXPENDITUREANDDETAILOFIT@NERARY- A@MOUNT CLA!M.EO (Deduct 1/1 from the applicah.@s per d;efn for each meal and todg;ng tunishe@, without 2 m DIEM OTHER IL 0-oo 29 ECK ONE: 2 TOTALI [IRICO FIJRWIRO 48.0;) 3.713 IT P ,r"'k- Ri'!PUIRED L;56 CONTINti"'t"O',V SHEET F'ORAT iVO. 922., IF ADDITIONA SSPA('-Iv "77' REQUEST-FOR--ADVANCE Dkm 6 Do L 19.1 1. -IT -IS REQUESTED THAT C04F IDENT IAL FUNDS BE ADVANCED TO: "W- NjkKg I N--THE- AMOUNT OF 2 DOLLARS S 2. THESE FUNDS ARE REQUINED FOR OFFICIAL BUSINESS OF A COMFI-DENTIAL I(ATURE-ANO THEIR USE WILL BE CONFINED TO THE FOLLOWING GENERAL PURPOSE: Ila) THIS ADVANCE IS WITHI! THE SCOPE OF.-AND PROPERLY CHARGEABLE TO AP pi[ 2avrd- P Ito it c T@i@--ALL C-IMZN T,@@ 4. THIS ADVANCE WILL BE ACCOUNTED FOR FULLY, IN ACCORDANCE WITH CONFIDENTIAL- FUNDS REGT)LATIONS, AND ALL U$EXPENDED FUNDS RETURNED, IN THE FOLLOWING MANNER: (COMPLETE AND/OR-lNlTIAL-APPLICABLE STATEMENT BELCW) 2 (A) WITHIN3.@L DAYS, ACCOUNTING AND/OR REFUND WILL BE MADE 10 CHIEF, CONFIDENTIAL FUNDS. (8) WITH[.-i-DAYS AFTER ARRIVAL AT DEST.KATION ACCOUNTING AND/OR REFUOD WILL BE MADE TO CONFIDENTIAL FUNDS REPRESENTATIYE AT A FULL ACCOUNTING WILL BE RENDERED AT-THE END OF EACH MONTH UNTIL ALL FU240S ARE ACCOUNTED FOR, SUCH ACCOUNTING WILL BE MADE TO THE CHIEF, CONFIDENTIAL FUNDS, OR TO HIS DESIGNATED REME$ENTATIVE. REQUESTING OFFICtA---- APPROVED: A CITW/ii D 2 TITLE @s I 6 @T U DATE 6- 1 CERTIFY that this request for advance is in accordance with existing regulations; has been approved Ly proper authority; and that funds are available in the apl)ropriation and allotf@,ocnt indicated. DATE -CP ikO Pl@l A Ti2 0 N ALLOTMENT CERTIFYIN5 QFF;C[.R RECEIVED FROM s 4W- ('J IN-T-@IE--FOR4-OF Catib FOR THE PURPOSE STATED. AID WILL BE ACCOUNTED FOR FULLY BY HE IN ACCOR.ANCE WITH PARAGRAPH 4 ABOVE. 2 uqh7 @v (Alf 4$ P*RVICUS lEbITIONS IIAY DIE TSCO. rolte iDt Cri@L i. Allol at O.? t4?@nr"...,i-.,-@. to