We're headed into a global depression-a period of economic misery that few living people have experienced. Depressions don't just generate ugly stats and send buyers and sellers into hibernation. They change the way we live. COVID-19 fears will bring lasting changes to public attitudes toward all activities that involve crowds of people and how we work on a daily basis; it will also permanently change America's competitive position in the world and raise profound uncertainty about U.S.-China relations going forward. Most postwar U.S. recessions have limited their worst effects to the domestic economy. But most were the result of domestic inflation or a tightening of national credit markets. That is not the case with COVID-19 and the current global slowdown. This is a synchronized crisis, and just as the relentless rise of China over the past four decades has lifted many boats in richer and poorer countries alike, so slowdowns in China, the U.S. and Europe will have global impact on our globalized world. The Congressional Budget Office has warned that the unemployment rate will remain stubbornly high for the next decade, and economic output will remain depressed for years unless changes are made to the way government taxes and spends. Those sorts of changes will depend on broad recognition that emergency measures won't be nearly enough to restore the U.S. economy to health. What's true in the U.S. will be true everywhere else.