A new study suggests the best way to get over a breakup is to fake it until you make it. Simply believing youre doing something positive to get over your ex can influence brain regions associated with emotional regulation and lessen the pain youre feeling. Remaining open to the possibility that what youre doing could potentially make you feel better works like a placebo. [Researchers at the University of Colorado Boulder] studied 40 young people whod experienced an unwanted breakup in the past six months. The participants were asked to bring in two photos: one of their ex and one of a close friend. Inside a functional magnetic resonance imaging (fMRI) machine, the heartbroken parties were shown images of their exes and asked to reflect on the breakup. Then they saw the images of their friend (the control variable). They were also given a jolt of physical pain (a hot stimulus on their left forearm). As these stimuli were alternately repeated ... the fMRI machine tracked activity in the brain. Similar areas of the brain lit up during both emotional pain ... and physical pain - suggesting that the heartache you feel after a breakup is very real. The subjects were [then] given a nasal spray. Half were told the spray was a powerful analgesic effective in reducing emotional pain, while the rest were told it was merely a saline solution. [After experiencing] the same painful stimuli as before ... the placebo group felt less physical and emotional pain, [and] there was reduced activity in the areas of the brain associated with social rejection.