In 2000 a study was published in the journal Regulatory Toxicology and Pharmacology that deemed the active ingredient in Roundup (glyphosate) was safe and not a human health risk. Since then, that study has been cited consistently as proof of Roundup's safety. Numerous other studies have shown that glyphosate could cause cancer and that the inert ingredients that are part of the patented Roundup formulation increase the toxicity of glyphosate. Further, the practice of using Roundup as a desiccant on small grain crops (oats, wheat and barley) prior to harvest, puts Roundup directly on grain that enters the human food chain. Since acquiring Monsanto in 2018, Bayer has paid out about $11 billion to settle almost 100,000 cancer-related lawsuits, with approximately 61,000 still pending. In December of 2025, another blow to the claimed safety of Roundup when the Regulatory Toxicology and Pharmacology journal withdrew the 2000 article that had touted Roundup's safety. While the study claimed to be independent and peer reviewed, it has come to light that Monsanto's scientists played a significant role in conceiving and writing the article. Oops. For decades, Roundup has been sold as an effective herbicide, one that was safe to humans and the environment and without it, "consequences would be dire". Companies like Bayer ... claim to produce safe products that help farmers thrive" real independent research refutes that.