Nearly three months into taking Ozempic for diabetes, Jenny Kent had already lost 12 pounds, and her blood sugar numbers were looking better than they had in a while. Ozempic, the injectable drug approved for Type 2 diabetes, has taken the world by storm. Despite not being approved by the Food and Drug Administration for weight loss, Ozempic has prompted people on TikTok and Instagram to speculate about which stars have used it to shed pounds seemingly overnight. But for Kent something else changed after she started taking Ozempic. I was just constantly in a state of being overwhelmed," says Kent. "So my response to that was just I was just crying all the time. Sobbing, crying ... I still didn't put it together, so I kept ... taking my injections." She's one of many people taking Ozempic and related drugs who describe mental health problems. But that side effect isn't mentioned in Ozempic's instructions for use, or drug label. In July, the European Medicines Agency said that it was looking into the risk of thoughts of self-harm and suicidal thoughts with the use of Ozempic and similar drugs. The FDA hasn't taken that step. NPR analyzed the FDA's adverse event reporting system, or FAERS, and learned that the agency has received 489 reports of patients experiencing anxiety, depression or suicidal thoughts while taking semaglutide drugs, including Ozempic, Wegovy and Rybelsus. In 96 of those reports, the patient had suicidal thoughts. Five of them died.