Bay Area researchers are beginning the first major U.S. study into a mystery disease known for its frightening symptoms - among them, open sores and unidentifiable objects poking out of the skin - that doctors have long suspected is all in patients' heads. The study into Morgellons will start immediately. The research will be funded by the U.S. Centers for Disease Control and Prevention [and conducted by Kaiser Permanente]. Researchers are hoping to come up with a more specific definition of Morgellons and how prevalent it is in the Bay Area, which has one of the largest concentrations of ... cases of the disease in the country. The CDC is not yet agreeing that Morgellons is a medical condition. Many doctors believe that Morgellons is actually a psychiatric condition called delusional parasitosis. They say the filaments that patients report growing out of their skin are actually lint or threads from clothing, and the open sores are caused by patients scratching at skin when they perceive a crawling sensation. San Francisco resident Pat Miller has been to more than a dozen doctors since he first developed symptoms several years ago. He's been diagnosed with a wide variety of skin conditions, as well as delusional parasitosis, and few doctors have been willing to consider Morgellons. I've developed this lack of love for doctors and health care systems. You pretty much have to become your own doctor." The nonprofit Morgellons Research Foundation says that more than 10,000 families in the United States have registered with the Web site, claiming at least one family member has the disease. About 24 percent of registered families are in California, and the Bay Area is one of several hot spots in the country. The research foundation estimates that 150 to 500 people in Northern California have Morgellons.