A second manufacturer is beginning mass production of a vaccine to protect against bird flu, and the Senate moved Thursday to invest far more -- $8 billion -- on preparations in case the influenza strain ever sparks a worldwide epidemic. Before the Senate acted, Health and Human Services Secretary Mike Leavitt awarded a $62.5 million contract to Emeryville, Calif.-based Chiron Corp. to manufacture bird flu vaccine. Sanofi-Aventis of Paris began manufacturing $100 million worth of a similar vaccine last month. The Bush administration is putting the final touches on its plan for how to fight the next super-flu...amid growing concern that the H5N1 influenza strain spreading among birds from Asia to Europe could trigger a pandemic if it mutates into a form easily spread from person to person. The massive out-of-budget expenditure...would increase stockpiles of the antiviral drugs Tamiflu and Relenza, thought to be effective against current strains of bird flu. The money that we spend now will not be wasted even if this particular strain of the virus, H5N1, ends up not becoming a pandemic flu," said Sen. Barack Obama, D-Ill. "We know that over the next two, three decades there will be a pandemic flu. That's almost certain."