Picture this: While reaching for the cookie jar - or cigarette or bottle of booze or other temptation - a sudden slap denies your outstretched hand. When the urge returns, out comes another slap. Now imagine those slaps" occurring inside the brain. In a report published Monday in the Proceedings of the National Academy of Sciences, Stanford neuroscientists say they've achieved this sort of mind-reading in binge-eating mice. They found a telltale pattern of brain activity that comes up seconds before the animals start to pig out - and delivering a quick zap to that part of the brain kept the mice from overindulging. Whether this strategy could block harmful impulses in people remains unclear. The current study used a brain stimulation device already approved for hard-to-treat epilepsy. And based on the new findings, a clinical trial testing this off-the-shelf system for some forms of obesity could start as early as next summer, says Casey Halpern, the study's leader. He thinks the approach could also work for eating disorders and a range of other addictive or potentially life-threatening urges. As a physician-researcher, Halpern specializes in deep brain stimulation (DBS), a surgical treatment in which battery-powered implants send electrical pulses to brain areas where signals go awry. The Food and Drug Administration has approved DBS therapy for movement disorders such as Parkinson's disease, tremor and dystonia. Occasionally DBS is a last-resort treatment for obsessive-compulsive disorder (OCD).