A cure for diabetes could be imminent after scientists discovered how to make huge quantities of insulin-producing cells, in a breakthrough hailed as significant as antibiotics. Harvard University has, for the first time, managed to manufacture the millions of beta cells required for transplantation. It could mean the end of daily insulin injections for the 400,000 people in Britain living with Type 1 diabetes. And it marks the culmination of 23-years of research for Harvard professor Doug Melton who has been trying to find a cure for the disease since his son Sam was diagnosed with Type 1 diabetes as a baby. We are now just one pre-clinical step away from the finish line," said Prof Melton. The stem cell-derived beta cells are presently undergoing trials in animal models, including non-human primates, where they are still producing insulin after several months, Prof Melton said. The team at Harvard used embryonic stem cells to produce human insulin-producing cells equivalent in almost every way to normally functioning cells in vast quantities. A report on the work is published in the journal Cell.
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