Over a period of 30 years, highly qualified Perth-based surgeon Dr John Holt has had some startling successes with a radio-wave therapy treatment for cancer patients. Dr Holt's controversial treatment works, in layperson's terms, by giving the patient an injection of a glucose-blocking agent. He then shines radio waves" into the body at a specific frequency. Dr Holt doesn't guarantee it will cure every cancer, but it's not expensive and there's no quackery about it. Born in Bristol 80 years ago and a member of the Royal Colleges, Dr Holt has 26 medical letters after his name. For more than a decade he was in charge of Western Australia's main cancer institute, until the late '70s, when he was blacklisted by his medical colleagues and politicians. The polarisation of the medical and scientific community in Perth over Dr Holt's treatment has been evident since the mid-'70s. While the medical community continues to argue the merits of Dr Holt's unorthodox measures, the families of his successes feel they owe everything to this gentle man. After two brain tumours and a tumour on her spine, Sophia Rosa was sent by pre-eminent brain surgeon Dr Charlie Teo for the radical treatment. Two years later, the only sign Sophia had cancer are the side-effects from the massive doses of chemotherapy given in Sydney.