A horrifying ... disease is affecting thousands of people in the Bay Area, along the Gulf Coast and in Florida. Though some doctors have claimed the malady is psychosomatic, other scientists are making headway unraveling the mystery of Morgellons Disease. Former Oakland A's pitcher Billy Koch has it. And so do his wife and their three children. It started in Oakland four years ago. Koch saved 44 games and was the top reliever in the major leagues. Within two years -- at age 29 -- Billy Koch was out of baseball, partly because of the uncontrollable muscle twitching that went on for months at a time and often kept up him up all night. The disease is characterized by slow-healing skin lesions that often extrude small, dark filaments, especially after bathing. More than 3,000 families nationwide [report] these same unexplained symptoms. Oklahoma State University Professor Randy Wymore was the first scientist to conduct research on this disconcerting disease. He says it's the biggest mystery he's ever been involved in. The UC Davis-trained physiologist is leading a medical team at Oklahoma State University in Tulsa. With cooperation from the Centers for Disease Control and Prevention, Wymore's team is studying Bay Area patients and others from around the country. His first finding disputes the frequent diagnosis of delusions. He says the filaments are not an external contamination. Instead, they are a substance that materializes somehow inside the body, apparent artifacts of something infectious. More results are expected soon. And Wymore says skin problems are not the worst symptoms. He says a neurotoxin or microorganism may disturb muscle control and memory. The neurological effects are the much more severe, life altering and much more dangerous of the conditions."