Not many 25-year-olds can claim to get up at 4am and work weekends to save the world from an impending Armageddon that could cost tens of millions of lives. But for the past three years, Shu Lam, a Malaysian PhD student at the University of Melbourne, has confined herself to a scientific laboratory to figure out how to kill superbugs that can no longer be treated with antibiotics. She believes that she has found the key to averting a health crisis so severe that last week the United Nations convened its first ever general assembly meeting on drug-resistant bacteria. The overuse and incorrect use of antibiotics has rendered some strains of bacteria untreatable, allowing so-called "superbugs" to mutate. Last Wednesday, the problem was described by UN Secretary-General Ban Ki-moon as a "fundamental threat" to global health and safety. [Lam] believes her method of killing bacteria using tiny star-shaped molecules, built with chains of protein units called peptide polymers, is a ground-breaking alternative to failing antibiotics. Her research, published this month in the prestigious journal, Nature Microbiology, has already been hailed by scientists as a breakthrough that could change the face of modern medicine. Lam successfully tested the polymer treatment on six different superbugs in the laboratory, and against one strain of bacteria in mice. Even after multiple generations of mutations, the superbugs have proven incapable of fighting back.
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