Nick was 19 when a psychiatrist offered him the antidepressant Trintellix to treat his moderate anxiety and depression after just a few short visits. Going on the popular selective serotonin reuptake inhibitor (SSRI) ... didn't seem like a big deal at the time. But, when Nick went off the medication after six years, he immediately noticed his genitals were losing sensation. Over the course of a couple weeks, he almost entirely lost feeling in the area and it never returned, nor did the high sex drive he once had. He would ultimately learn he suffers from Post-SSRI Sexual Dysfunction (PSSD). "I wasn't at risk of taking my own life or anything like that … I still had a hell of a lot of fun in life … I think I definitely should have [done] therapy first and foremost," he said. "Now there's just no enjoyment in anything. It's like watching a brick wall." For many, antidepressants are lifesaving treatments, but, in rare instances, they can potentially cause debilitating side effects that persist for years after stopping the drugs. SNOMED, the National Institute Of Health's official source of medical terminology for US healthcare systems, recognizes PSSD as a legitimate disorder as of last year, defining it as "persistent sexual side effects" including genital numbness and loss of libido that "can last for weeks, months, or even years after stopping" antidepressants. The rate of prescriptions for those ages 12 to 25 jumped by about two-thirds from 2016 to 2022. "The studies that were done for SSRIs to be approved by the FDA were not done on children, they were done on adults," [clinical psychologist Meg Jay] said. "But now it's much more common for tweens and teens to be prescribed medications than it used to be." In the past two years alone, [Psychopharmacologist and former professor of psychiatry David Healy] said he's known more than a dozen people, many of them young, who were so distressed by PSSD that they committed suicide.