Stephen Ross spends most of his time helping people quit drugs. But early next year, he will begin administering MDMA in his ... medical research lab. MDMA, aka ecstasy, will still be an illegal drug. But it's emerging as one of the most promising treatments for intractable post-traumatic stress disorder. Rick Doblin ... encountered MDMA for the first time [in 1982]. Two years later, he watched a patient suffering from PTSD undergo MDMA-assisted therapy. That completely persuaded me of its therapeutic potential," Doblin says. In 1985, Doblin learned that the DEA was moving to ban the drug ... and founded a nonprofit - the Multidisciplinary Association for Psychedelic Studies - to fight the prohibition. In 2000 [Doblin] met Michael Mithoefer, a therapist specializing in PTSD. Mithoefer had grown frustrated by the available treatments. Mithoefer and his wife and co-therapist, Annie, conducted the first MAPS-funded Phase II trial in 2004, which used MDMA to treat PTSD in victims of rape and childhood sexual abuse. These were patients with chronic cases that had proved resistant to other treatment methods. A second group, made up of veterans, firefighters and police officers, followed. Therapists refer to MDMA as an empathogen - something that enables patients to feel empathy not just for others but also for themselves. Of the 90 people who completed the 12-month follow-up after Phase II, 68% of them "did not meet PTSD criteria," according to the study results MAPS submitted to the FDA. Of the remaining third, many had some reduction in symptoms.
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