Top officials at the Centers for Disease Control and Prevention received premium bonuses in recent years at the expense of scientists and others who perform much of the agency's scientific work. Those inside the office of the centers' director, Dr. Julie L. Gerberding, have benefited the most. From 2002 through mid-2006, William H. Gimson III, the agency's chief operating officer, received bonuses totaling $147,863. Before Dr. Gerberding's appointment, members of the C.D.C. director's inner circle rarely received premium bonuses. Because bonus money is limited...the growing share of premium bonuses for Dr. Gerberding's closest advisers has meant less money is available for some scientists and other workers. In addition to those within Dr. Gerberding's inner circle, the increase in large cash awards within the centers has mostly benefited employees in the agency's financial, computer and human resources departments -- not its scientists. Soon after arriving at the centers, Dr. Gerberding began a comprehensive reorganization of the agency. In its wake, many of the agency's senior scientists and leaders either left or have announced that they are planning to leave. The Washington Post and The Atlanta Journal-Constitution have reported on the turmoil at the centers in articles quoting disgruntled former senior scientists who said the changes had undermined the agency.