When she was in high school, Lizzie Velasquez was dubbed The World's Ugliest Woman" in an 8-second-long YouTube video. Born with a medical condition so rare that just two other people in the world are thought to have it, Velasquez has no adipose tissue and cannot create muscle, store energy, or gain weight. She has zero percent body fat and weighs just 60 pounds. In the comments on YouTube, viewers called her "it" and "monster" and encouraged her to kill herself. Instead, Velasquez set four goals: To become a motivational speaker, to publish a book, to graduate college, and to build a family and a career for herself. Now 23 years old, she's been a motivational speaker for seven years and has given more than 200 workshops on embracing uniqueness, dealing with bullies, and overcoming obstacles. She's a senior majoring in Communications at Texas State University in San Marcos, where she lives with her best friend. Her first book, Lizzie Beautiful, came out in 2010 and her second, Be Beautiful, Be You, was published earlier this month. She's even reclaimed YouTube, video blogging about everything from bullying to hair-styling tips to staying positive. Of course, the horrible comments left on that old YouTube video stung. "I'm human, and of course these things are going to hurt," she said. "Their judgments of me isn't who I am, and I'm not going to let these things define me. I didn't sink down to their level," she said in a follow-up video on YouTube last year. "Instead, I got my revenge through my accomplishments and determination. In the battle between the 'World's Ugliest Woman' video vs. me, I think I won."