Hallucination-inducing drugs like magic mushrooms could be about to break big pharma's stranglehold on the hugely lucrative market for antidepressants, according to the head of the world's first centre for psychedelic research. Antidepressant prescriptions have doubled in England in a decade with around seven million adults taking the drugs, and the global market is predicted to be worth $15.9bn (12.5bn) by 2023. At Imperial College London, Dr Robin Carhart-Harris is leading one of the first trials to test how therapy using psilocybin mushrooms, which are currently banned in the UK, compares to leading antidepressants. While he won't prejudge the results of the study, he says participants describe a cathartic emotional "release" with psilocybin therapy - the polar opposite of antidepressants, which patients complain leave their emotions, whether positive or negative, "blunted". It is the first of many studies planned under the banner of the new Centre for Psychedelic Research at London's Imperial College. Dr James Rucker is another of those researching the potential benefits of psychedelics ... at King's College London. The King's team are launching two trials, one looking at whether psilocybin therapy can help people whose depression is resistant to treatment with conventional antidepressants. He says it was "possible" the drug could be licensed in five years.