This week, life sciences company COMPASS Pathways announced that it has received "Breakthrough Therapy" designation from the United States Food and Drug Administration for its psilocybin therapy aimed at individuals with treatment-resistant depression. Psilocybin, the main active ingredient in psychedelic mushrooms ... can alter one's perception, thoughts and feelings or cause hallucinations. Researchers from Switzerland, the United Kingdom and the U.S. have been studying the therapy for many years. In fact, a study published in January found that the psychoactive compound helped revive emotional responsiveness in patients with treatment-resistant depression. Another showed that patients' mental benefits after two psilocybin treatments lasted for weeks. COMPASS Pathways will begin running the first large-scale psilocybin clinical trial for treatment-resistant depression in Europe and North America within the next two years. "This is great news for patients," COMPASS executive chairman George Goldsmith said. "We are excited to be taking this work forward with our clinical trial. The FDA will be working closely with us to expedite the development process and increase the chances of getting this treatment to people suffering with depression as quickly as possible." While treatments such as antidepressants and psychotherapy exist, those with severe, treatment-resistant depression ... have trouble finding help. Approximately 100 million around the globe are affected by such treatment-resistant depression.