MDMA is the main ingredient in club drugs ecstasy or molly. But [Lori] Tipton wasn't taking pills sold on the street to get high at a party. She was trying to treat her post-traumatic stress disorder, with the help of licensed therapists. Two specially-trained psychotherapists ... sat next to Tipton as she recalled some of her deepest traumas, like discovering her mother's body after a murder-suicide. I was able to find such empathy for myself. I realized how much I was thinking this was my fault," she says. The synthetic psychoactive chemical MDMA is emerging as a promising - if unconventional - treatment for PTSD. Scientists are testing how pharmaceutical-grade MDMA can be used in combination with psychotherapy to help patients who have a severe form of PTSD that has not responded to other treatments. It's not yet available as a treatment for PTSD outside of clinical trials, but the success of early trials has proponents hopeful that the therapy could be available to more people in coming years. They're aiming for approval by the The Food and Drug Administration, which granted breakthrough therapy status to MDMA-assisted psychotherapy in 2017. After the Phase 2 trials of MDMA-assisted treatments concluded in 2017, researchers found 54% of the patients who took MDMA had improved to the point that they no longer fit the diagnosis for PTSD (compared to 23% in the control group). A year later, the number who no longer had PTSD had risen to 68% percent.
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