Poison control centers across the US say they are seeing a steep increase in calls related to semaglutide, an injected medication used for diabetes and weight loss, with some people reporting symptoms related to accidental overdoses. Some have even needed to be hospitalized for severe nausea, vomiting and stomach pain, but their cases seem to have resolved after they were given intravenous fluids and medications to control nausea. From January through November, the America's Poison Centers reports nearly 3,000 calls involving semaglutide, an increase of more than 15-fold since 2019. In 94% of calls, this medication was the only substance reported. In most of the calls, people reported dosing errors, said Dr. Kait Brown, clinical managing director of the association. "Oftentimes, it's a person who maybe accidentally took a double dose or took the wrong dose," Brown said. Semaglutide was approved by the US Food and Drug Administration in 2017. It is sold as Ozempic when used for diabetes and Wegovy when used for weight loss. Even when used as directed by a doctor, people can have stomach and bowel side effects, including nausea, vomiting and constipation, especially when they start the drugs. After celebrities began openly embracing Ozempic on social media in 2022 as a way to lose weight, demand overwhelmed supply. There's no specific antidote for a semaglutide overdose.
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