For most, psychedelic drugs conjure up images of the 1960's, hippies tripping out on LSD or magic mushrooms. But ... these powerful, mind-altering substances are now being studied seriously by scientists inside some of the country's foremost medical research centers. They're being used to treat depression, anxiety and addiction. The early results are impressive, as are the experiences of the studies' volunteers who go on a six-hour, sometimes terrifying, but often life-changing psychedelic journey. For nearly two decades now, [scientist Roland Griffiths] and his colleague Matthew Johnson have been giving what they call heroic doses" of psilocybin to more than 350 volunteers, many struggling with addiction, depression and anxiety. Carine McLaughlin was a smoker for 46 years and said she tried everything to quit before being given psilocybin at Johns Hopkins last year. That was more than a year ago; she says she hasn't smoked since. The study she took part in is still ongoing, but in an earlier, small study of just 15 long-term smokers, 80% had quit six months after taking psilocybin. That's double the rate of any over-the-counter smoking cessation product. Jon Kostakopoulos was drinking a staggering 20 cocktails a night ... when he decided to enroll in another psilocybin trial at New York University. During one psilocybin session, he was flooded with powerful feelings and images from his past. He took psilocybin in 2016. He says he hasn't had a drink since.