A disgraced former British surgeon's new documentary about the discredited link between autism and childhood vaccination has put Robert De Niro at the centre of a medical row that threatens the reputation of his prestigious film festival in New York. De Niro, the father of an autistic child and co-founder of the Tribeca film festival, is standing by the decision to premiere Vaxxed: from Cover-Up to Catastrophe, which has been directed by the controversial Andrew Wakefield. The trailer for Wakefield's film opens with ominous music as the words "Are our children safe?" appear through a spiral of billowing smoke seeping from a syringe. A key element of the documentary, the trailer claims, will be the testimony of a whistleblower from the Centers for Disease Control and Prevention, the US public health body, who is to allege fraud inside an organisation that "knew that vaccines were actually causing autism". De Niro and his wife, Grace Hightower, issued a statement on Friday, defending the screening. "Grace and I have a child with autism and we believe it is critical that all of the issues surrounding the causes of autism be openly discussed and examined. In the 15 years since the Tribeca film festival was founded, I have never asked for a film to be screened or gotten involved in the programming. "However this is very personal to me and my family and I want there to be a discussion, which is why we will be screening Vaxxed.