Leading chemical experts are calling for a radical overhaul of chemical regulation to protect children from everyday toxins that may be causing a global ''silent epidemic'' of brain development disorders such as autism, dyslexia and attention-deficit hyperactivity disorder. A review published in The Lancet Neurology on [February15] said current regulations were inadequate to safeguard fetuses and children from potentially hazardous chemicals found in the environment and everyday items such as clothing, furniture and toys. In the past seven years, the number of recognised chemical causes of neurodevelopmental disorders doubled from six to 12. These include lead, arsenic, pesticides such as DDT, solvents, methylmercury that is found in some fish, flame retardants that are often added to plastics and textiles, and manganese - a commonly mined metal that can get into drinking water. The list also controversially includes fluoride, a mineral found in water, plants and toothpaste. Many health authorities including the World Health Organisation and ... governments say low levels of fluoride in drinking water is safe and protects teeth against decay, but [the researchers] said a meta-analysis of 27 studies, mainly from China, had found children in areas with high levels of fluoride in water had significantly lower IQ scores than those living in low-level fluoride areas. Since 2006, the number of chemicals known to damage the human brain more generally, but that are not regulated to protect children's health, had increased from 202 to 214. Of the newly identified toxins, pesticides constitute the largest group.