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Inside Medicine: Is your doctor giving you this important number?
Key Excerpts from Article on Website of Sacramento Bee (Leading newspaper of California's capital city)


Sacramento Bee (Leading newspaper of California's capital city), May 5, 2007
Posted: May 14th, 2007
http://www.sacbee.com/107/story/166505.html

By Dr. Michael Wilkes. I recently wrote a column about cholesterol-lowering medications. I stated that if 67 healthy men with elevated cholesterol took a cholesterol-lowering drug ... for five years, only one would benefit. The other 66 would not benefit, and it would cost about $5,500 over the five-year period. I received a ton of e-mail from readers. Many readers wrote that after knowing this number, they did not feel taking the drug was worth the effort or expense. Others took the opposite view. Both interpretations are valid, depending on the person's values. This number -- the 1 in 67 -- is a term doctors call "the number needed to treat," or NNT. It is a relatively new concept [that] is grossly underused in sharing information with the public. Doctors and pharmacists do a poor job talking with patients about their medications. Many people will derive little or no benefit from their medicines, but they are never told this. The key is for doctors and patients to understand the NNT. Here are some estimates of NNT: 1 in 2,550: The number of breast cancer deaths prevented in women between the ages of 50 and 59 screened annually for five years with mammograms. 1 in 2,000: The number of women ages 60-64 without risk factors who would prevent a hip fracture by taking medicine for osteoporosis for five years. 1 in 700: The number of people with mild high blood pressure who would prevent a stroke or heart attack by taking blood pressure medicine for one year. 1 in 16: The number of infections prevented by treating a victim of a dog bite with a week of antibiotics. 1 in 7: The number of children (otherwise healthy children) who benefit from treatment with an antibiotic for an ordinary ear infection.

Note: Many doctors and scientists have made valid claims that drug companies are hyping disease in order to make profits on their drugs. For a top MD's discussion of this vital topic, click here.


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