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Expect new drugs to treat aging, researchers say
Key Excerpts from Article on Website of Atlanta Journal-Constitution/Cox News Service
Posted: June 10th, 2008
http://www.ajc.com/services/content/health/stories/2008/06/0...
Is 90 the new 50? Not yet, aging researchers say, but medical breakthroughs to significantly extend life and ease the ailments of getting older are closer than many people think. "The general public has no idea what's coming," said David Sinclair, a Harvard Medical School professor who has made headlines with research into the health benefits of a substance found in red wine called resveratrol. He said scientists can greatly increase longevity and improve health in lab animals like mice, and that drugs to benefit people are on the way. "It's not an if, but a when." Sinclair said treatments could be a few years or a decade away, but they're "really close. It's not something (from) science fiction and it's not something for the next generation." Robert Butler, a pioneer of aging research who won the Pulitzer Prize in 1976 for the book Why Survive? Being Old in America, [said] that "people live longer and better by having a sense of purpose." He said that while medicine and biology are important for longevity, having friendships and close relationships also have a big impact. Richard Weindruch, a professor at the University of Wisconsin ... studies how extremely low-calorie diets affect aging. Sinclair said that based on Weindruch's work, he set out a decade ago to find the genes involved in caloric restriction and find a pill that can provide the benefits "without you feeling hungry all the time." He described how his research found that mice given large doses of resveratrol "live longer, they're almost immune to the effects of obesity. They don't get diabetes, cancer, Alzheimer's as frequently. We delay the diseases of aging."