Cancer Cures News ArticlesExcerpts of key news articles on cancer cures
There are no magic bullets in the fight against cancer: that's the first thing every responsible scientist mentions when discussing a possible new treatment, no matter how promising. If there were a magic bullet, though, it might be something like dichloroacetate, or DCA, a drug that kills cancer cells by exploiting a fundamental weakness found in a wide range of solid tumors. So far, though, it kills them just in test tubes and in rats infected with human cancer cells; it has never been tested against cancer in living human beings. DCA ... is an existing drug whose side effects are well-studied and relatively tolerable. Also, it's a small molecule that might be able to cross the blood-brain barrier to reach otherwise intractable brain tumors. Within days after a technical paper on DCA appeared in the journal Cancer Cell last week, the lead author, Dr. Evangelos Michelakis of the University of Alberta, was deluged with calls and e-mails from prospective patients—to whom he can say only, “Hang in there.” DCA is a remarkably simple molecule. It acts in the body to promote the activity of the mitochondria. Researchers have assumed that the mitochondria in cancer cells were irreparably damaged. But Michelakis wondered if that was really true. With his colleagues he used DCA to turn back on the mitochondria in cancer cells—which promptly died. One of the great things about DCA is that it's a simple compound, in the public domain, and could be produced for pennies a dose. But that's also a problem, because big drug companies are unlikely to spend a billion dollars or so on large-scale clinical trials for a compound they can't patent.
Note: Read a 2010 follow-up by Dr. Michelakis with promising results and watch a 10-minute video. Explore the DCA website. Why didn't other mass media report this major story? Why aren't many millions of dollars being poured into research? Notice even Newsweek acknowledges the drug companies are not interested in finding a cure for cancer if they can't make a profit from it. Some suspect the drug companies have even suppressed cancer cures found in the past. See one amazing example of this. For more, see these major media articles on potential cancer cures.
We could make faster progress against cancer by changing the way drugs are developed. In the current system, if a promising compound can’t be patented, it is highly unlikely ever to make it to market — no matter how well it performs in the laboratory. The development of new cancer drugs is crippled as a result. The reason for this problem is that bringing a new drug to market is extremely expensive. In 2001, the estimated cost was $802 million; today it is approximately $1 billion. To ensure a healthy return on such staggering investments, drug companies seek to formulate new drugs in a way that guarantees watertight patents. In the meantime, cancer patients miss out on treatments that may be highly effective and less expensive to boot. In 2004, Johns Hopkins researchers discovered that an off-the-shelf compound called 3-bromopyruvate could arrest the growth of liver cancer in rats. The results were dramatic; moreover, the investigators estimated that the cost to treat patients would be around 70 cents per day. Yet, three years later, no major drug company has shown interest in developing this drug. The hormone melatonin, sold as an inexpensive food supplement in the United States, has repeatedly been shown to slow the growth of various cancers when used in conjunction with conventional treatments. Early this year, another readily available industrial chemical, dichloroacetate, was found by researchers at the University of Alberta to shrink tumors in laboratory animals by up to 75 percent. However ... dichloroacetate is not patentable, and the lead researcher is concerned that it may be difficult to find funding from private investors to test the chemical. Potential anticancer drugs should be judged on their scientific merit, not on their patentability.
Note: To explore several cancer cures which have shown dramatic potential, yet are not being studied for lack of funds due to inability to patent the process, click here. Why are these very promising treatments not being fast-tracked as the expensive AIDS drugs were? For a top MD's revealing comments on this, click here. And for why the media won't feature these promising cancer treatments in headlines, click here.
Researchers say they have created a drug that has killed every kind of cancer tumor it has come in contact with, according to Science Magazine. The antibody treatment works by blocking a protein called CD47 which tricks the body into not destroying cancerous cells. After the protein is blocked, the body can then recognize the cancer cells as invaders and attack. While the research is seen as a step closer to discovering a treatment that can cure all cancers, the drug has only been tested on mice and will need to prove itself on humans before it can be available to patients. This may take a few years. The research team has been given the green light and recently received a four-year, $20 million grant to conduct human clinical trials. Research for this new drug started a decade ago when biologist Irving Weissman at Stanford University was studying leukemia cells. He found that that leukemia cells produce higher levels of the CD47 protein than healthy cells. CD47 acts as a "don't-eat-me" signal, instructing the body to not eat harmful cells. Cancers take advantage of this signal to trick the immune system into ignoring them. Weissman's research showed that blocking CD47 can cure more than just blood cancers. The drug can also shrink or cure human breast, ovary, colon, bladder, brain, liver and prostate tumors that have been transplanted into mice. The treatment forced the mice's immune system to kill the cancer cells. This means this single drug could cure a variety of cancers and prevent cancers from spreading in the body.
Note: With many millions around the world dying of cancer every year, why aren't the most promising treatments being fast-tracked? Why is this article titled a "rumor"? Why isn't this making major headlines? Why isn't the very promising treatment of DCA, which is both cheap and incredibly promising, being given many millions to move rapidly forward? To read major media articles describing other potential cures not being adequately funded, click here. To understand why some treatments are suppressed, click here.
Last winter, inventor John Kanzius was already attempting one seemingly impossible feat -- building a machine to cure cancer with radio waves -- when his device inadvertently succeeded in another: He made saltwater catch fire. TV footage of his bizarre discovery has been burning up the blogosphere ever since, drawing crackpots and Ph.D.s alike into a raging debate. Can water burn? And if so, what good can come of it? Some people gush over the invention's potential for desalinization or cheap energy. Briny seawater, after all, sloshes over most of the planet's surface, and harnessing its heat energy could power all sorts of things. Skeptics say Kanzius's radio generator is sucking up far more energy than it's creating, making it a carnival trick at best. For now, Kanzius is tuning out the hubbub. Diagnosed with leukemia in 2002, he began building his radio-wave blaster the next year, soon after a relapse. If he could seed a person's cancerous cells with nanoscopic metal particles and blast them with radio waves, perhaps he could kill off the cancer while sparing healthy tissue. The saltwater phenomenon happened by accident when an assistant was bombarding a saline-filled test tube with radio waves and bumped the tube, causing a small flash. Curious, Kanzius struck a match. "The water lit like a propane flame," he recalls. "People said, 'It's a crock. Look for hidden electrodes in the water,' " says Penn State University materials scientist Rustum Roy, who visited [Kanzius] in his lab in August after seeing the feat on Google Video. A demo made Roy a believer. "This is discovery science in the best tradition," he says. Meanwhile, researchers at MD Anderson Cancer Center in Houston and the University of Pittsburgh Medical Center have made progress using Kanzius's technology to fight cancer in animals. They published their findings last month in the journal Cancer.
Note: For other compelling articles on this fascinating invention, see recent articles in the Los Angeles Times, ABC News, and especially Medical News Today. And for dozens of astounding major media articles showing clear suppression of potential cancer cures, click here.
In a new study, researchers found that breast-cancer patients who had high levels of vitamin D were twice as likely to survive [as] women with low levels. They reviewed five studies that observed more than 4,440 women. “The study has implications for including vitamin D as an adjuvant to conventional breast cancer therapy,” study co-author Dr. Heather Hofflich, an associate professor of medicine at the University of California San Diego, said in a press release. The researchers recommend that vitamin D should be added to the various treatments given to women fighting breast cancer. The body naturally produces vitamin D when exposed to sunlight, but milk, fatty fish and other foods can also boost production. Patients could also take vitamin D supplements.
Note: This is huge news! Why isn't this exciting development getting more press coverage? Read numerous major media articles revealing potential cancer cures which have received little attention. And see an excellent article with more on the Vitamin D connection.
Sixteen-year-old Jack Andraka's innovative mind led him to create a new way to detect pancreatic, ovarian and lung cancer. "I created a new way to detect pancreatic, ovarian and lung cancer that costs three cents and takes five minutes to run," he said. After a close friend died from pancreatic cancer, this 16-year-old from Crownsville, Maryland, unleashed his hyper-drive intellect on preventing more cancer deaths. "It's 168 times faster, over 26,000 times less expensive, and over 400 times more sensitive than our current methods of diagnosis," he said. Tinkering in his room and using information readily available online, he came up with a new way to detect cancer. "85 percent of all pancreatic cancers are diagnosed late, when someone has less than a two percent chance of survival. And our current test costs $800 per test and misses 30 percent of all pancreatic cancers," he said. He won last year's Intel International Science and Engineering Fair. The sweet validation came with $100,000 in scholarships, but Jack Andraka's got his eye on even bigger things. "The name of the competition is called the Tricorder XPRIZE," he said. "It's a $10 million prize. Essentially what you have to do is develop something the size of a smartphone that you scan over your skin and it will diagnose any disease instantly." Jack is fielding a team of other high-schoolers to compete against 300 teams of adult scientists and corporations in the Qualcomm Tricorder XPRIZE competition. He says youth is an advantage -- that new eyes are more likely to solve old problems.
Note: Let's hope this invention gets fast tracked and makes it to market. Notice how little attention this exciting development received. To read about many potential cancer cures reported in major media which have not made it to market for financial reasons, click here. For a treasure trove of great news articles which will inspire you to make a difference, click here.
Eric Merola's "Burzynski" charts how a Texas medical doctor and biochemist developed Antineoplastons, genetic-targeted medicines, and with them began to treat a wide range of cancers, including difficult-to-treat brain malignancies, with remarkable and continuing success only to bring down the full force of the medical establishment, which has laid assault to him in the most stupefying, devious and costly manner. Stanislaw Burzynski, a Polish immigrant ... eventually won a 14-year struggle – during which he found himself threatened with life imprisonment and astronomical fines for fraud and other violations – to obtain FDA-approved clinical trials of his Antineoplastons, an ordeal that cost Burzynski $2.2 million in legal expenses and the FDA $60 million in taxpayers' money. The film makes the case that big pharmacy holds the FDA in its thrall. Burzynski's Antineoplastons, with their high success rate and lack of side effects, pose a significant threat to the trillion-dollar industry of treating cancer with the traditional methods of surgery, radiation and chemotherapy.
Note: The Los Angeles Times now requires payment to view this article at this link. For the Burzynski clinic website, click here. You can watch part or all of this revealing movie at this link. For another powerful documentary featuring a variety of potential cancer cures that have been suppressed, click here. For excerpts from numerous major media articles with potential cancer cures that are being suppressed, click here.
In a major breakthrough in the search for a cure for cancer, the first human trials are to begin using a technique that has already been shown to destroy the disease in mice. The trials are the culmination of years of research prompted by the discovery of a cancer-proof mouse by researchers almost a decade ago. More than 20 cancer patients will be given white blood cells with cancer-killing properties in an attempt to boost their immune system's fight against the deadly illness. The work stems from experiments into the metabolism of a humble laboratory mouse whose immunity to cancer defied the repeated attempts of scientists to kill it with high-level doses of cancer cells. White blood cells taken from the animal and its offspring were subsequently used to cure other mice of advanced cancers. The white blood cells destroyed the cancer cells but left normal cells alone. This discovery encouraged scientists to study how people might be helped to fight off cancer by being given a boost of white blood cells called granulocytes. Laboratory tests have since shown how human granulocytes can destroy cervical, prostate and breast cancer cells, provided sufficient numbers of cancer-killing granulocytes from healthy donors are used. Scientists are now confident that the treatment will prove just as successful in humans as it has been in mice. Hundreds of donors will be recruited for the new treatment – which is called leukocyte infusion therapy – and a process similar to platelet donation will be used to collect the granulocytes.
White blood cells from mice that are naturally immune to cancer cured tumors in other mice and provided them with lifelong immunity to the disease, researchers reported Monday. The finding indicates the existence of a biological pathway previously unsuspected in any species. A small team of researchers is working to understand the genetic and immunological basis of the surprising phenomenon. Preliminary studies hint at the existence of a similar resistance in humans. Researchers hope that harnessing the biological process could lead to a new approach to treating cancer. But Dr. Zhen Cui of Wake Forest, whose team published the findings in the Proceedings of the National Academy of Science, said he expected rapid replication of the results because the findings were so clear-cut and easily observed. "This is a truly remarkable phenomenon -- and it really needs confirmation from other institutions," he said. The team took white blood cells from the immune mice ... and injected them into mice already carrying a variety of tumors, some of which were extremely aggressive. In every case, the cancers were destroyed, even if the cells were injected at a point distant from the tumor. Healthy tissues were not affected. The mice that received the cells, furthermore, were protected from new tumors for the rest of their lives. The researchers have no idea how the immunity continues.
Note: Why was this not in the headlines and not given a title like "Cancer Cure Found for Mice"? Most major papers didn't even report the story, and an article in the New York Times was titled simply "A Strain of Mice Appears Able to Resist Cancer Cells." Could it be that the power brokers in the medical industry know that a cancer cure would cause huge financial losses for them? For what happened to an incredible scientist in the past who discovered a cancer cure for humans, click here.
Germs that cause cancer have been discovered and with a new high-frequency radio "ray." They have been killed in human patients who then recovered, according to assertions made yesterday at the California State Homeopathic Medical society’s convention. The new progress in combating malignant cancer is said to have been made possible by an ultra microscope that magnifies 31,000 times and by a ray that kills micro-organisms in humans. Both the microscope and the Ray were developed by Royal Raymond Rife of San Diego. Rife was to have announced his discoveries before the British Medical Society, but made the announcement locally because of the war. Dr. Arthur W. Yale of San Diego reported that with the aid of the Rife Ray he has succeeded in curing a number of cases of malignant cancer in which patients had been told they had only a limited time in which to live. The physician [said that] "for 17 years Mr. Rife experimented with vibratory waves of all frequencies, and he has now succeeded in finding a rate that will kill the different invading organisms of the body. Radio waves, which with their harmonics range from 10 meters to 20,000 meters, are projected through a tube filled with helium gas. I have witnessed the disappearance of every malignant growth when the patient has remained under treatment." Dr. Yale then reported case histories of patients treated. Mr. Rife alluded to the fact that the medical profession has not yet accepted his findings. “My work may not be accepted during my lifetime," he said, "but ... I know it ultimately will be recognized.
Note: As the above link requires payment, you can read the full text of this article free at this link. For an abundance of powerful, verifiable information on this amazing man and how his cancer cure was ruthlessly suppressed by the medical establishment, click here.
A small team of Israeli scientists is telling the world they will have the first “complete cure” for cancer within a year, The Jerusalem Post reported. And not only that, but they claim it will be brief, cheap and effective and will have no or minimal side-effects. “We believe we will offer in a year’s time a complete cure for cancer,” said Dan Aridor, chairman of the board of Accelerated Evolution Biotechnologies Ltd. (AEBi), a company founded in 2000 in ... Ness Ziona, Israel. A development-stage biopharmaceutical company engaged in discovery and development of therapeutic peptides, AEBi developed the SoAP platform, a combinatorial biology screening platform technology, which provides functional leads—agonist, antagonist, inhibitor, etc. - to very difficult targets. Called MuTaTo (multi-target toxin), researchers said the drug is essentially "on the scale of a cancer antibiotic a disruption technology of the highest order." Aridor told The Jerusalem Post: “Our cancer cure will be effective from day one, will last a duration of a few weeks and will have no or minimal side-effects at a much lower cost than most other treatments on the market. Our solution will be both generic and personal.” Currently in development ... the potential game-changer in the world-wide fight against cancer will use a combination of cancer-targeting peptides and a toxin that will specifically kill cancer cells. Every sixth death in the world is due to cancer, making it the second leading cause of death, second only to cardiovascular disease.
Note: Yet even in this article the attacks on these scientists have already begun. The cancer industry does not want to lose literally billions of dollars in profits. For more on this, see the Royal Rife story. For more along these lines, see concise summaries of deeply revealing major media news articles on other cancer treatments with high promise which were suppressed.
High-dose vitamin C can boost the cancer-killing effect of chemotherapy in the lab and mice, research suggests. Given by injection, it could potentially be a safe, effective and low-cost treatment for ovarian and other cancers. US scientists ... call for large-scale government clinical trials. Vitamin C has long been used as an alternative therapy for cancer. In the 1970s, chemist Linus Pauling reported that vitamin C given intravenously was effective in treating cancer. However, clinical trials of vitamin C given by mouth failed to replicate the effect, and research was abandoned. It is now known that the human body quickly excretes vitamin C when it is taken by mouth. However, scientists at the University of Kansas say that when given by injection vitamin C is absorbed into the body, and can kill cancer cells without harming normal ones. The researchers injected vitamin C into human ovarian cancer cells in the lab, into mice, and into patients with advanced ovarian cancer. They found ovarian cancer cells were sensitive to vitamin C treatment, but normal cells were unharmed. The treatment worked in tandem with standard chemotherapy drugs to slow tumour growth. "Because vitamin C has no patent potential, its development will not be supported by pharmaceutical companies," said lead researcher Qi Chen. "We believe that the time has arrived for research agencies to vigorously support thoughtful and meticulous clinical trials with intravenous vitamin C."
Note: Read more about this amazing cancer research. For more along these lines, see concise summaries of deeply revealing news articles on promising cancer research that has been suppressed by the medical industry.
Doctors have known that low levels of vitamin D are linked to certain kinds of cancers as well as to diabetes and asthma, but new research also shows that the vitamin can kill human cancer cells. The results fall short of an immediate cancer cure, but they are encouraging, medical professionals say. JoEllen Welsh, a researcher with the State University of New York at Albany, has studied the effects of vitamin D for 25 years. Part of her research involves taking human breast cancer cells and treating them with a potent form of vitamin D. Within a few days, half the cancer cells shriveled up and died. Welsh said the vitamin has the same effect as a drug used for breast cancer treatment. "Vitamin D enters the cells and triggers the cell death process," she [said]. "It's similar to what we see when we treat cells with Tamoxifen," a drug used to treat breast cancer. The vitamin's effects were even more dramatic on breast cancer cells injected into mice. After several weeks of treatment, the cancer tumors in the mice shrank by an average of more than 50 percent. Some tumors disappeared. Similar results have been achieved on colon and prostate cancer tumors in mice.
In a study, researchers have found that long-term pot smokers were roughly 62 percent less likely to develop head and neck cancers than people who did not smoke pot. The new study featured 434 patients with head and neck cancers, which include tumors in the mouth, tongue, nose, sinuses, throat and lymph nodes in the neck, and 547 individuals without these cancers seen in the Greater Boston area from December 1999 to December 2003. After factoring out the impact of smoking, drinking, and other factors that might influence the results, smoking marijuana from once every two weeks to three times every two weeks, on average, was associated with about half the risk of head and neck cancer, compared with less frequent use. Those who took up pot smoking at an older age appeared to have less risk of these cancers than those who started it at a younger age. Compared to people who never smoked pot, those who began smoking marijuana between the ages of 15 and 19 years were 47 percent less likely to develop head and neck cancer, while users who began at age 20 or older had a 61 percent reduced risk, Kelsey and colleagues found. The authors note that chemicals in pot called cannabinoids have been shown to have potential antitumor effects. Other studies have linked marijuana use to a reduced risk of some cancers, such as cancer of the prostate, and now head and neck cancer. It's also been suggested that smoking pot may help stave off Alzheimer's disease and help combat weight loss associated with AIDS, and nausea and vomiting associated with chemotherapy in cancer patients.
Note: For a great nine-minute video presenting major media reports showing how marijuana is a very promising cancer treatment that is being suppressed, click here. For deeply revealing reports from reliable major media sources on health issues, click here.
In what a dying Rick Smalley called the most important application from his Nobel Prize-winning discovery [of fullerines], Houston researchers are using [carbon] nanotubes heated by radio waves to kill cancer cells. In a paper posted online by the journal Cancer, a team at the University of Texas M.D. Anderson Cancer Center and Rice University reported that the technique destroyed liver cancer tumors in rabbits and caused no side effects. It is thought to hold the same potential for many other cancers. "I don't want to overstate matters — I'm the biggest skeptic in the world — given the challenges still ahead of us," Dr. Steven Curley, an M.D. Anderson surgical oncologist and the paper's senior author, said Thursday. "But my hope is that this will be a very useful tool to safely and efficiently treat a lot of types of cancer." The therapy marries two disparate disciplines: the relatively ancient field of radio waves and nanotechnology, the cutting-edge science of the ultra-small. The rabbit study found the therapy worked only when the two were used together. It works not by poisoning but by creating a localized hyperthermia — or small fever — that destroys the cancer cells' membranes, protein and even DNA. The cells then die and are carried out of the body through normal kidney functions. In the experiment recounted in Cancer, the rabbits were injected with a solution of single-walled carbon nanotubes — hollow cylinders of pure carbon measuring about a billionth of a meter across — then exposed to two minutes of radio-frequency treatment. The result, researchers said, was the thermal destruction of 100 percent of the tumors. The idea was inspired by John Kanzius, an M.D. Anderson leukemia patient and retired Pennsylvania radio and television station owner. He developed a radio-frequency generator after undergoing chemotherapy and noting its effect on himself and other patients.
Note: For many hopeful new developments in the search for cancer cures, click here.
Government nutrition researcher [Dr. Mark Levine] has published new evidence that suggests vitamin C can work like chemotherapy - only better. But so far, he hasn't been able to interest cancer experts in conducting the kind of conclusive studies that, one way or the other, would advance treatment. "If vitamin C is useful in cancer treatment, that's wonderful. If it's not, or if it's harmful, that's fine, too," said Levine, a Harvard-educated physician at the National Institute of Diabetes and Digestive and Kidney Diseases. The distinction between oral and intravenous is crucial. The body automatically gets rid of extra C through urine. Levine's lab has shown that, at high concentrations, the vitamin is toxic to many types of cancer cells in lab dishes. But to get that much C into the body before it's eliminated, it must be put directly into the blood. Five out of nine types of cancer cells that were put in simulated body-cavity fluid died when concentrated ascorbate or peroxide was added to the dish. And the best part: This same lethal marinade had no effect on healthy cells. "Interest is definitely growing," said Kenneth Bock, physician and president of the American College for Advancement in Medicine, an alternative-medicine society that teaches ascorbate infusion protocols. The American Cancer Society and the American Association of Clinical Oncologists warn patients against high-dose C, as do leading cancer centers such as the University of Pennsylvania's and Memorial Sloan-Kettering.
Scientists have created a new cowpox-style virus in a bid to cure cancer. The treatment, called CF33, can kill every type of cancer in a petrie dish and has shrunk tumours in mice, The Daily Telegraph reported. US cancer expert Professor Yuman Fong is engineering the treatment, which is being developed by Australia biotech company Imugene. They are hoping the treatment will be tested on breast cancer patients, among other cancer sufferers, next year. Professor Fong is currently in Australia to organise the clinical trials, which will also be run overseas. Patients with triple negative breast cancer, melanoma, lung cancer, bladder, gastric and bowel cancer would be tested in the 'basket study'. The virus, which causes the common cold, was turned into a treatment for brain cancer by scientists in the US. The cancer in some patients disappeared for years before it came back, while others saw tumours shrink considerably. Similarly, a form of the cold sore virus called Imlygic or T-Vec was found to be able to treat melanoma, as it helped the body's immune system recognise and destroy tumours and melanoma cells in the body. Cancer patients would have the engineered virus injected directly into their tumours for the breakthrough treatment. It's hoped the virus would infect the cancer calls and make them explode. The immune system is then expected to be alerted about other cancer cells in the body, prompting the diseased cells to be killed.
Note: For more along these lines, see concise summaries of deeply revealing news articles on promising cancer research from reliable major media sources.
You can protect yourself from cancer by eating organic. Those who frequently eat organic foods lowered their overall risk of developing cancer, a study published Monday in JAMA Internal Medicine finds. Specifically, those who primarily eat organic foods were more likely to ward off non-Hodgkin lymphoma and postmenopausal breast cancer compared to those who rarely or never ate organic foods. A team of researchers looked at the diets of 68,946 French adults. More than three-quarters of the volunteers were women, in their mid-40s on average. Comparing the participants' organic food scores with cancer cases, the researchers calculated a negative relationship between high scores (eating the most organic food) and overall cancer risk. Those who ate the most organic food were 25% less likely to develop cancer. Specifically, they were 73% less likely to develop non-Hodgkin lymphoma and 21% less likely to develop post-menopausal breast cancer. Even participants who ate low-to-medium quality diets yet stuck with organic food experienced a reduced risk of cancer, the authors found. The authors theorize a "possible explanation" for the negative relationship between organic food and cancer risk stems from the "significant" reduction of contamination that occurs when conventional foods are replaced by organic foods. The new findings are consistent with those of the International Agency for Research in Cancer, which found pesticides are cancer causing in humans
Note: For more along these lines, see concise summaries of deeply revealing news articles on food corruption from reliable major media sources. Then explore the excellent, reliable resources provided in our Health Information Center.
A vaccine injected into a tumor triggers the immune system to kill cancer, a new study in mice confirms. Stanford researchers have now begun seeking human patients who want to help test this approach. The research behind this potential new cancer treatment was published Wednesday in Science Translational Medicine. Cancer vaccines work a bit differently than a vaccine against the measles or the flu. Those shots are meant to train an immune system to target an infection before the virus or bacteria arrives. Cancer vaccines, however, are given after a person is diagnosed. This shot ... combines two components: a short piece of DNA molecules that can stimulate the immune system to create greater quantities of a receptor called OX40 and a protein that sticks to those receptors, prompting the immune cells to attack the tumor. [Study co-author Dr. Ronald Levy] and his colleagues tested their vaccine in more than 90 mice, some with a tumor transplanted into them and others that were genetically primed to develop cancer. However, the next step in this research will go well beyond mice. Levy and his colleagues have begun looking for about 15 people with lymphoma to test the vaccine in a clinical trial. If the trials are successful, he believes it could help people with a wide variety of cancers. “I don’t think there’s a limit to the type of tumor we could potentially treat, as long as it has been infiltrated by the immune system,” he stated.
High doses of vitamin C injected into the blood stream could prove effective in treating cancer, according to new research. Scientists said vitamin C infusions, which were up to 1,000 times higher than recommended intake levels, selectively targeted tumour cells in cancer patients. This increased the rates of cell deaths and sensitised them to radiation and chemotherapy. The treatment also appeared to be safe, producing mild side effects such as frequent bathroom trips and a dry mouth. Eleven brain cancer patients were given three infusions of vitamin C a week for two months followed by a further two per week for seven months while receiving standard radiotherapy and chemotherapy. Tests showed that iron in their tumours reacted with the vitamin to form highly reactive and destructive “free radical” hydrogen peroxide molecules. The free radicals were thought to cause selective DNA damage in cancerous, but not healthy, cells. This in turn was expected to lead to enhanced cancer cell death as well as sensitisation to radiation and chemotherapy drugs. US researcher Dr Garry Buettner, from the University of Iowa, said: “This paper reveals a metabolic frailty in cancer cells that is based on their own production of oxidizing agents that allows us to utilise existing redox active compounds, like vitamin C, to sensitise cancer cells to radiation and chemotherapy.” The safety study sets the stage for larger Phase II trials investigating whether high-dose vitamin C injections can extend the lifespan of cancer patients.
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