A nondescript office building just a short walk from the Limmat River - which runs through the picturesque center of Zurich, Switzerland - houses the hub of Helvetas Swiss Intercooperation. The effect of the nongovernmental organization, however, is anything but ordinary. "We work for the poorest," says Rupa Mukerji, co-head of advisory services for Helvetas and a member of its management board. The organization operates in 32 countries to address rural poverty, harnessing a $150 million annual budget and the efforts of some 1,500 staffers, more than 95 percent of whom are local to their projects. That mission is personal to Ms. Mukerji. "I am supporting a program in Mali where we are investing our own resources to develop a climate change plan," she explains. "Many times climate change is seen as an issue of science ... but communities are already feeling the impact," she says. Her home country of India has been suffering from serious drought - something she sees as showing why her work is so critical. "When you work at the field level, you see how hard [people] work, how difficult the conditions are. Many things they are facing are completely out of their control," she says. "My passion lies in really addressing these global challenges, and to make life better for the people in these rural communities."