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Tending the Bodys Microbial Garden
Key Excerpts from Article on Website of New York Times
Posted: January 8th, 2013
http://www.nytimes.com/2012/06/19/science/studies-of-human-m...
For a century, doctors have waged war against bacteria, using antibiotics as their weapons. But that relationship is changing as scientists become more familiar with the 100 trillion microbes that call us home collectively known as the microbiome. I would like to lose the language of warfare, said Julie Segre, a senior investigator at the National Human Genome Research Institute. It does a disservice to all the bacteria that have co-evolved with us and are maintaining the health of our bodies. This new approach to health is known as medical ecology. Rather than conducting indiscriminate slaughter, Dr. Segre and like-minded scientists want to be microbial wildlife managers. No one wants to abandon antibiotics outright. But by nurturing the invisible ecosystem in and on our bodies, doctors may be able to find other ways to fight infectious diseases, and with less harmful side effects. Tending the microbiome may also help in the treatment of disorders that may not seem to have anything to do with bacteria, including obesity and diabetes. Last week, Dr. Segre and about 200 other scientists published the most ambitious survey of the human microbiome yet. Known as the Human Microbiome Project, it is based on examinations of 242 healthy people tracked over two years. The scientists sequenced the genetic material of bacteria recovered from 15 or more sites on their subjects bodies, recovering more than five million genes. The project and other studies like it are revealing some of the ways in which our invisible residents shape our lives, from birth to death.
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