Mind-Altering Drugs News ArticlesExcerpts of Key Mind-Altering Drugs News Articles in Media
Charles Grob [is] a psychiatrist and researcher at Harbor-U.C.L.A. Medical Center who [has administered] psilocybin — an active component of magic mushrooms — to end-stage cancer patients to see if it could reduce their fear of death. When the research was completed in 2008 ... the results showed that administering psilocybin to terminally ill subjects could be done safely while reducing the subjects’ anxiety and depression about their impending deaths. Grob’s interest in the power of psychedelics to mitigate mortality’s sting is not just the obsession of one lone researcher. Dr. John Halpern, head of the Laboratory for Integrative Psychiatry at McLean Hospital in Belmont Mass., a psychiatric training hospital for Harvard Medical School, used MDMA — also known as ecstasy — in an effort to ease end-of-life anxieties in two patients with Stage 4 cancer. And there are two ongoing studies using psilocybin with terminal patients, one at New York University’s medical school, led by Stephen Ross, and another at Johns Hopkins Bayview Medical Center, where Roland Griffiths has administered psilocybin to 22 cancer patients and is aiming for a sample size of 44. “This research is in its very early stages,” Grob told me earlier this month, “but we’re getting consistently good results.” Grob and his colleagues are part of a resurgence of scientific interest in the healing power of psychedelics.
Note: For fascinating reports from major media sources on the beneficial uses of psychedelics, click here.
A 50-year mystery over the 'cursed bread' of Pont-Saint-Esprit, which left residents suffering hallucinations, has been solved after a writer discovered the US had spiked the bread with LSD as part of an experiment. In 1951, a quiet, picturesque village in southern France was suddenly and mysteriously struck down with mass insanity and hallucinations. At least five people died, dozens were interned in asylums and hundreds afflicted. For decades it was assumed that the local bread had been unwittingly poisoned with a psychedelic mould. Now, however, an American investigative journalist has uncovered evidence suggesting the CIA peppered local food with the hallucinogenic drug LSD as part of a mind control experiment at the height of the Cold War. One man tried to drown himself, screaming that his belly was being eaten by snakes. An 11-year-old tried to strangle his grandmother. Another man shouted: "I am a plane", before jumping out of a second-floor window, breaking his legs. He then got up and carried on for 50 yards. Many were taken to the local asylum in strait jackets.
As more states legalize marijuana, there's growing interest in a cannabis extract — cannabidiol, also known as CBD. It's marketed as a compound that can help relieve anxiety - and, perhaps, help ease aches and pains, too. CBD doesn't have the same mind-altering effects as marijuana, since it does not contain THC, the psychoactive component of the plant. "There's good evidence to suggest that CBD could be an effective treatment of anxiety and addiction" and other disorders, says Dr. Esther Blessing, a psychiatrist and researcher at New York University. "But we need clinical trials." Small, short-term human studies ... suggest CBD exhibits anti-inflammatory and anti-anxiety properties. These preliminary findings piqued Blessing's interest. For instance, she points to a 2011 study of a few dozen people, some of whom had social anxiety disorder, who were asked to speak in front of a large audience. Researchers compared anxiety levels in people after they took CBD, compared to those who got the placebo or nothing at all. "People who took CBD reported significantly less anxiety" compared to those who got the placebo, Blessing says. Though CBD supplements are widely available for sale, a legal murkiness surrounds marijuana extracts. Even if you live in a state where marijuana use is legal, the federal Drug Enforcement Administration still classifies the CBD extract as a Schedule 1 substance — the DEA's most restricted category.
Note: Read more about the use of CBD to treat epilepsy and other serious conditions. For more along these lines, see concise summaries of deeply revealing health news articles from reliable major media sources.
In the last few years, calls for marijuana to be researched as a medical therapy have increased. It may be time for us to consider the same for psychedelic drugs. Two general classes of such drugs exist, and they include LSD, psilocybin, mescaline and ecstasy (MDMA). All are illegal in the United States, [and can] cause harm. The best-known adverse event is persistent flashbacks, though these are believed to be rare. More common are symptoms like increased heart rate and blood pressure, anxiety and panic. Some people have pointed to ... positive effects. People with life-threatening illnesses can also suffer from anxiety, which is hard to treat. In 2014, a small randomized controlled trial was published that examined if LSD could be used to improve this anxiety. Anxiety was significantly reduced in the intervention group for up to a year. More common are studies of the use of psychedelics to treat abuse or addiction to other substances. [One study] exploring LSD’s potential to treat alcoholism [found that] alcohol use and misuse were significantly reduced in the LSD group for six months. Similar studies using psilocybin have also shown promising results. Researchers [have also] examined the potential for MDMA in the treatment of chronic and treatment-resistant post-traumatic stress disorder. At two months after therapy, more than 80 percent of those in the treatment group saw a clinical improvement versus only 25 percent of those in the placebo group. The beneficial effects lasted for at least four years, even with no further treatment.
Note: Read more about how MDMA has been found effective for treating PTSD in a therapeutic context. Articles like this suggest that the healing potentials of mind-altering drugs are beginning to gain mainstream scientific credibility.
For a long time, Daniel Au Valencia got the message that she was wrong, wrong, wrong. “There’s a lot of shame around autism,” she says. Last year Valencia heard about an unusual experimental study ... exploring a treatment specifically for social anxiety in autistic adults. Many traditional therapies don’t work for autistic people, says Nick Walker, [a] consultant on the new study, because they reinforce stigma around autism. He sees this new research as a uniquely “culturally appropriate” approach to addressing the “epidemic” of social anxiety in autistic adults. The treatment is MDMA, known more commonly as Ecstacy or Molly. Early studies ... show it can ease or erase symptoms of post-traumatic stress disorder. In one study, 83 percent of study participants treated with MDMA and psychotherapy were cured of their PTSD. Psychologist Alicia Danforth [is] conducting the social anxiety study at UCLA’s Los Angeles Biomedical Research Institute, along with psychiatrist Charles Grob. Valencia is one of just 12 autistic adults participating in the pilot study. It’s impossible to draw a direct line between the treatment and how Valencia is doing right now, but she says she’s doing great. She’s got a steady full-time job, her own apartment, and she just got married. She says her biggest takeaway ... is more about emotions than social anxiety. She says she’s learned that there’s no such thing as good emotions or bad emotions. “All emotions deserve to exist,” she says.
Note: Learn more about the healing potentials of mind-altering drugs now being explored by the scientific community.
Marijuana and the Veterans Affairs Hospital system’s relationship is complicated. On the one hand, 23 states plus the District of Columbia say marijuana is legal for sanctioned medical use, and veterans are clamoring for it for their post-combat symptoms. On the other, marijuana is classified a Schedule I drug. Veterans [have] been stuck in the middle. As many as 20 percent of veterans from Iraq and Afghanistan suffer from post-traumatic stress disorder. Antidepressants like Zoloft and Paxil, along with other heavy-duty pills, have been the traditional mainstays in VA doctors’ arsenals. Non-FDA approved options, marijuana among them, haven’t been options at all. But that has started to change. The Veterans Equal Access Act ... aims to open the entire VA system to judicious prescription of medical cannabis. Prior to its introduction, VA doctors couldn’t even discuss cannabis with their patients, much less prescribe it. Arizona psychiatrist Sue Sisley [has] spent two decades treating patients with PTSD. “All we have now is Zoloft and Paxil. And if you know much about those meds, you know there are many side effects, and they often don’t work. If they are effective, then patients are dealing with these side effects,” Sisley adds. “Vets come home from service, and they just want to reintegrate into their family. And we make them fat and impotent and mired in a bunch of disabling side effects.” When asked why marijuana might be better than other options, Sisley’s quick to answer: “A single plant can provide monotherapy for this whole constellation of symptoms.”
Imagine discovering a plant that has the potential to help alleviate post-traumatic stress disorder, suicidal thoughts and paralyzing anxiety. That's what some believe ayahuasca can do, and this psychedelic drink is attracting more and more tourists to the Amazon. War vets are seeking it for PTSD. Former Marine Lance Cpl. Ryan LeCompte organizes trips to Peru for war veterans, like himself, who are seeking ayahuasca as a possible treatment for PTSD and other emotional and mental trauma suffered after multiple combat deployments. "Ayahuasca is a way to give relief to those who are suffering," says LeCompte, who says many veterans are not satisfied with the PTSD treatment they receive when they return from combat. Libby ... is one of the veterans who accompanied LeCompte to Peru to try ayahuasca for her PTSD diagnosis, which includes sexual trauma while on active duty. She says antidepressants made her more suicidal. "I would like to wish not to die all the time," she said, when asked why she was seeking ayahuasca. "I want that to go away." Those of have tried ayahuasca say that any benefits - like with other drugs or medicine - must be combined with therapy. There are efforts to study the medicinal benefits of ayahuasca, explains Rick Doblin, executive director of the Multidisciplinary Association of Psychedelic Studies. "At a time when drug policy is being reevaluated ... how ayahuasca should be handled in a regulatory context is really up in the air," Doblin said.
Note: Watch the full CNN documentary on an ayahuasca ceremony in Peru. For more along these lines, see these concise summaries of deeply revealing news articles about mind altering drugs from reliable sources.
[There are many] obstacles and frustrations scientists face in trying to study the medical uses of marijuana. Dating back to 1999, the Department of Health and Human Services has indicated it does not see much potential for developing marijuana in smoked form into an approved prescription drug. In guidelines issued that year for research on medical marijuana, the agency quoted from an accompanying report that stated, “If there is any future for marijuana as a medicine, it lies in its isolated components, the cannabinoids and their synthetic derivatives.” Scientists say this position has had a chilling effect on marijuana research. Though more than one million people are thought to use the drug to treat ailments ranging from cancer to seizures to hepatitis C and chronic pain, there are few rigorous studies showing whether the drug is a fruitful treatment for those or any other conditions. A major reason is this: The federal government categorizes marijuana as a Schedule 1 drug, the most restrictive of five groups established by the Controlled Substances Act of 1970. Drugs in this category — including heroin, LSD, peyote and Ecstasy — are considered to have no accepted medical use in the United States and a high potential for abuse, and are subject to tight restrictions on scientific study. In the case of marijuana, those restrictions are even greater than for other controlled substances. Marijuana remains illegal under federal law, though nearly half the states and the District of Columbia allow its medical use and two, Colorado and Washington, have legalized its recreational use.
Note: For more on this, see concise summaries of deeply revealing government corruption news articles from reliable major media sources.
Psychedelic drug research is coming back. But the research still faces stigma, and funding is hard to get. Stanislav Grof was one of the leading researchers on the therapeutic applications of LSD in the 1950s and '60s. He studied the effect of hallucinogens on mental disorders, including addiction. Grof tells NPR's Arun Rath, "This was a tremendous deepening and acceleration of the psychotherapeutic process. Compared with the therapy in general, which mostly focuses on suppression of symptoms, here we had something that could actually get to the core of the problems." The Schedule 1 classification of LSD and other hallucinogenic substances in 1970 was a huge blow to research. But by the '90s, attitudes had begun to change. By the 2000s, a small but growing research community was picking up where Grof and others had left off. One area that showed promise was using hallucinogens to ease anxiety and depression in patients with cancer, like Erica Rex. "I was diagnosed with breast cancer, stage 2, in 2009," Rex says. "I went through the treatment, and then there are some drugs that have terrible side effects." She says she became obsessed with the possibility of her death, and it was crippling. Then Rex [was approved] for a study on the experimental drug psilocybin, an active compound in psychedelic mushrooms. In the end, she says, it helped her depression.
Note: Food justice champion Michael Pollan recently wrote a fascinating article prominently featured in the venerable magazine The New Yorker about the amazing power of psilocybin mushrooms to create profound healing in carefully controlled environments. It is subtitled "Research into psychedelics, shut down for decades, is now yielding exciting results." Are the healing potentials of mind altering drugs finally starting to receive honest mainstream attention?
When Noa Shulman came home from school, her mother, Yael, sat her down to eat, then spoon-fed her mashed sweet potatoes - mixed with cannabis oil. Noa is part of the first clinical trial in the world to test the benefits of medicinal marijuana for young people with autism, a potential breakthrough. There is anecdotal evidence that marijuana’s main non-psychoactive compound - cannabidiol or CBD - helps children in ways no other medication has. Now this first-of-its-kind scientific study is trying to determine if the link is real. Israel is ...one of just three countries with a government-sponsored medical cannabis program, along with Canada and the Netherlands. Conducting cannabis research is also less expensive here and easier under Israeli laws, particularly compared to the United States. Autism is one of the fastest-growing developmental disorders, affecting 1 in 68 children in the United States. Only two medications have been approved in the United States by the Food and Drug Administration to treat the symptoms of autism. Both are antipsychotic drugs that are not always effective and carry serious side effects. Adi Aran, the pediatric neurologist leading the study, said nearly all the participants previously took antipsychotics and nearly half responded negatively. Anecdotal reports of autistic children who benefited from cannabis ... led Aran to pursue more scientific testing. After seeing positive results in 70 of his autistic patients in an observational study, Aran said, “OK we need to do a clinical trial."
Note: Dozens of studies have found evidence that CBD can treat epilepsy as well as a range of other illnesses. While more people are arrested in the US for marijuana use than for all violent crimes combined and the US federal government continues to regard non-psychoactive CBD as a dangerous drug, the UK government recently announced it will regulate CBD as medicine. For more along these lines, see concise summaries of deeply revealing health news articles from reliable major media sources.
A psychedelic drink used for centuries in healing ceremonies is now attracting the attention of biomedical scientists as a possible treatment for depression. Researchers from Brazil last month published results from the first clinical test of a potential therapeutic benefit for ayahuasca, a South American plant-based brew. The work forms part of a renaissance in studying the potential therapeutic benefits of psychedelic or recreational drugs — research that was largely banned or restricted worldwide half a century ago. Ketamine, which is used medically as an anaesthetic, has shown promise as a fast-acting antidepressant; psilocybin, a hallucinogen found in ‘magic mushrooms’, can help to alleviate anxiety in patients with advanced-stage cancer; MDMA (ecstasy) can alleviate post-traumatic stress disorder; and patients who experience debilitating cluster headaches have reported that LSD eases their symptoms. Ayahuasca, a sacramental drink traditionally brewed from the bark of a jungle vine (Banisteriopsis caapi) and the leaves of a shrub (Psychotria viridis) ... has been studied by anthropologists, social scientists and theologians, but clinical research on ayahuasca has been limited to observation of its effects in mice and rats, and in healthy human volunteers, including brain-imaging studies and retrospective surveys of past use. Further trials are under way.
Note: Are the healing potentials of mind altering drugs finally starting to receive honest mainstream attention?
In July, the Food and Drug Administration took the important step of approving two final-phase clinical trials to determine whether a party drug that has long been on the Drug Enforcement Administration’s Schedule I list of banned substances could be used to treat a psychiatric condition that afflicts millions. The drug is MDMA, a psychedelic commonly known as Ecstasy. The trials aim to determine whether the drug is, as earlier trials have suggested, a safe and effective treatment for post-traumatic stress disorder. The F.D.A. approval is a beacon of hope for the roughly eight million Americans believed to suffer from PTSD, a group that includes victims of abuse, refugees and combat veterans. The shortcomings in the way we have typically treated PTSD mean that many are condemned to suffer from the condition for years, even decades, with little relief. Less than 20 percent of patients are estimated to get effective treatment through prescription psychiatric drugs ... which, along with psychotherapy, have been the global standard of mental health care since the 1990s. This could change with the F.D.A.’s decision, which has given MDMA-assisted psychotherapy for the treatment of PTSD the status of a potential “breakthrough therapy.” This designation permits the fast-tracking of trials in hopes of proving the drug, which has psychedelic and stimulant effects, to be safe and capable of doing what no other drug on the market can.
Note: Read more about how MDMA has been found to be highly effective for treating PTSD in a therapeutic context. Articles like this suggest that the healing potentials of mind-altering drugs are gaining mainstream scientific credibility.
More than half a century ago, author Aldous Huxley titled his book on his experience with hallucinogens The Doors of Perception. Huxley posited that ordinary consciousness represents only a fraction of what the mind can take in. In order to keep us focused on survival, Huxley claimed, the brain must act as a “reducing valve” on the flood of potentially overwhelming sights, sounds and sensations. What remains, Huxley wrote, is a “measly trickle of the kind of consciousness” necessary to “help us to stay alive.” A new study by British researchers supports this theory. It shows for the first time how psilocybin — the drug contained in magic mushrooms — affects the connectivity of the brain. Researchers found that the psychedelic chemical ... does not work by ramping up the brain’s activity as they’d expected. Instead, it reduces it. Under the influence of mushrooms, overall brain activity drops, particularly in certain regions that are densely connected to sensory areas of the brain. When functioning normally, these connective “hubs” appear to help constrain the way we see, hear and experience the world, grounding us in reality. Psilocybin cuts activity in these nodes and severs their connection to other brain areas, allowing the senses to run free. Huxley ... had predicted what turns out to be a key finding of modern neuroscience: many of the human brain’s highest achievements involve preventing actions instead of initiating them, and sifting out useless information rather than collecting and presenting it for conscious consideration.
Note: There are several excellent links in the full article which show promising results of using these plants to improve mental health and more.
The psychedelic drug psilocybin (the active ingredient in “magic mushrooms”) may produce lasting, positive changes in personality, new research finds. People who took the drug showed increases in the key personality dimension of openness — being amenable to new ideas, experiences and perspectives — more than a year later. Researchers led by Katherine MacLean, a postdoctoral student at Johns Hopkins University, analyzed personality data on 52 participants (average age 46) who had participated in the group’s earlier research on the drug. These volunteers took psilocybin during two to five sessions, at various doses, under highly controlled conditions at the hospital. The earlier study had found positive psychological changes — documented by both participants and their family members and other associates — in calmness, happiness and kindness. The new research found that the drug takers also saw long-term changes to their underlying personality. The personality changes also ran counter to those expected as people age. Normally, as people grow older, they become increasingly less open to new ideas and new experiences. In contrast, in participants who experienced had what researchers call a “full mystical experience,” the scientists saw a shift toward increased openness, as though the volunteers had become decades younger. People became more curious and more interested in new ideas and experiences and in trying new things.
In 2002, at a Johns Hopkins University laboratory, a business consultant named Dede Osborn took a psychedelic drug as part of a research project. She felt like she was taking off. She saw colors. Then it felt like her heart was ripping open. But she called the experience joyful as well as painful, and says that it has helped her to this day. "I feel more centered in who I am and what I'm doing," said Osborn, now 66, of Providence, R.I. "I don't seem to have those self-doubts like I used to have. I feel much more grounded (and feel that) we are all connected." Scientists reported ... that when they surveyed volunteers 14 months after they took the drug, most said they were still feeling and behaving better because of the experience. Two-thirds of them also said the drug had produced one of the five most spiritually significant experiences they'd ever had. The drug, psilocybin, is found in so-called "magic mushrooms." It's illegal, but it has been used in religious ceremonies for centuries. The project made headlines in 2006 when researchers published their report on how the volunteers felt just two months after taking the drug. The new study followed them up [to] a year after that. Fourteen months after taking the drug, 64 percent of the volunteers said they still felt at least a moderate increase in well-being or life satisfaction, in terms of things like feeling more creative, self-confident, flexible and optimistic. The questionnaire answers indicated lasting gains in traits like being more sensitive, tolerant, loving and compassionate.
Note: For lots of exciting reports on new health research, click here.
The Secret Intelligence Service, MI6, has paid thousands of pounds in compensation to servicemen who were fed LSD without their consent in clandestine mind-control experiments in the 1950s. MI6 has agreed an out-of-court settlement with the men, who said they were duped into taking part in the experiments and had waited years to learn the truth. Don Webb, a former airman, said yesterday: "I feel vindicated; this has been a classic cover-up for years." MI6's counterparts at the CIA also did LSD experiments on men without their knowledge to try to control their minds. Mr Webb said scientists gave him LSD at least twice in a week. He remembers a nightmarish experience when he hallucinated for a long time. He saw "walls melting, cracks appearing in people's faces ... eyes would run down cheeks, Salvador Dali-type faces ... a flower would turn into a slug". He said he had first made inquiries about the experiments in the 1960s but was "blanked by the government, which quoted the Official Secrets Act". He said he experienced flashbacks for 10 years after the experiments. "They treated us just like guinea pigs."
Fifty years ago, Eric Gow had a baffling and unexplained experience. As a 19-year-old sailor, he remembers going to a clandestine military establishment, where he was given something to drink in a sherry glass and experienced vivid hallucinations. Other servicemen also remember tripping: one thought he was seeing tigers jumping out of a wall, while another recalls faces "with eyes running down their cheeks, Salvador Dalí-style". Mr Gow and another serviceman had volunteered to take part in what they thought was research to find a cure for the common cold. Mr Gow felt that the government had never explained what happened to him. But now he has received an official admission for the first time, confirmed last night, that the intelligence agency MI6 tested LSD on servicemen. One of the scientists involved at the time suggested that the experiments were stopped because it was feared that the acid could produce "suicidal tendencies". MI6, known formally as the Secret Intelligence Service (SIS) and responsible for spying operations abroad, carried out the tests in the cold war in an attempt to uncover a "truth drug" which would make prisoners talk against their will in interrogations. In parallel experiments, the CIA infamously tested LSD and other drugs on unwitting human subjects in a 20-year search to uncover mind-manipulation techniques. The trials were widely criticised when they came to light in the 1970s.
Note: For key reports from major media sources on CIA experimentation on unwitting subjects, click here.
Decades after the U.S. Federal Government banned the drug ecstasy — which in turn went underground, gaining notoriety as a party drug — a Bay Area medical team got special permission to study its therapeutic use. The goal of the trial is to see whether a pure dose of the compound MDMA, also known as ecstasy, can be pure medicine: could it ease the crippling anxiety, fear, or depression felt by those suffering from a life-threatening disease? The lead investigator for this study is psychiatrist Phil Wolfson. The medical doctor has permission from the U.S. FDA to conduct the study, and legally administer the drug. “The FDA approved so the DEA had to follow suit,” explained Wolfson. Before the DEA declared MDMA illegal in 1985, Doctor Wolfson used it medicinally in his own practice and saw a tremendous benefit for patients. In the study, MDMA is not used alone. The use of the compound is combined with psychotherapy sessions that can last five hours or longer. “It’s not this 50 minutes in and out, it’s these extended periods of real interactive exchange, “ explained [study participant Andy] Gold. “With the MDMA, everything opened up,” recalled [study participant Wendy] Donner. “You start seeing things very, very clearly and at a nice slow pace, truths in your life are bubbling up. And revealed to you piece by piece,” explained [study participant John] Saul. The participants all say they’ve changed and are better able to face the future. Wolfson hopes the drug may one day be available to other patients as a legally accepted remedy.
Dozens of adults and children, all clad in white, stood in a line. A holy man handed each a cup of ayahuasca, a muddy-looking hallucinogenic brew. Among those imbibing from the holy man’s decanter were prison inmates, convicted of crimes such as murder, kidnapping and rape. “I’m finally realizing I was on the wrong path in this life,” said Celmiro de Almeida, 36, who is serving a sentence for homicide. “Each experience helps me communicate with my victim to beg for forgiveness,” said Mr. de Almeida. The provision of a hallucinogen to inmates ... reflects a continuing quest for ways to ease pressure on Brazil’s prison system. The country’s inmate population has doubled since the start of the century ... straining underfunded prisons rife with human rights violations. Around , Acuda, a pioneering prisoners’ rights group in Porto Velho, began offering inmates therapy sessions in yoga, meditation and Reiki. Two years ago, the volunteer therapists at Acuda had a new idea: Why not give the inmates ayahuasca as well? Acuda had trouble finding a place where the inmates could drink ayahuasca, but they were finally accepted by an offshoot here of Santo Daime, a Brazilian religion founded in the 1930s. “Many people in Brazil believe that inmates must suffer,” said Euza Beloti, 40, a psychologist with Acuda. “This thinking bolsters a system where prisoners return to society more violent than when they entered prison.” At Acuda, she said, “we simply see inmates as human beings with the capacity to change.”
While [Ketamine] has been used as an anesthetic for decades, small studies at prestigious medical centers like Yale, Mount Sinai and the National Institute of Mental Health suggest it can relieve depression in many people who are not helped by widely used conventional antidepressants like Prozac or Lexapro. And the depression seems to melt away within hours, rather than the weeks typically required for a conventional antidepressant. Pharmaceutical companies hope to [develop] drugs that work like ketamine but without the side effects, which are often described as out-of-body experiences. Some doctors and patients are not waiting for the pharmaceutical industry. Because ketamine has long been approved for anesthesia, doctors are allowed to use it off-label to treat depression. ”There is clearly a need for new drugs. “Almost half of depressed patients are not being treated adequately by existing drugs,” said Dr. Sheldon H. Preskorn, a professor of psychiatry at the University of Kansas School of Medicine-Wichita. That, he said, is because virtually all the antidepressants used in the last 60 years work essentially the same way. Ketamine would represent a new mechanism of action. “Synaptic connections that help us to cope seem to grow back,” said Dr. John H. Krystal, chairman of psychiatry at Yale and a pioneer in the study of ketamine for depression.
Note: A 2012 NPR story provides more detail about the ketamine research done at Yale to treat depression. Could this put a stop to the thousands of horror stories involving conventional antidepressants?
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