Parkinson's [is] a movement disorder that causes tremors, stiffness and balance problems. A 2008 meta-analysis found that placebos used in clinical trials of Parkinson's treatments improved symptoms by an average of 16%. [A] team from the University of Cincinnati ... had a hunch that patients would be more responsive to a fake drug they thought was real if it came with a heftier price tag. So they recruited 12 patients with moderately advanced" Parkinson's and asked them to participate in a clinical trial. The study volunteers were told that there were two versions of the experimental drug and that both were believed to work equally well, [but] one version cost 15 times more than the other. In reality, both placebos were composed of the exact same saline solution. And yet, the patients perceived the expensive version to be more effective than the cheaper one, according to results published Wednesday in the journal Neurology. Both of the placebos improved motor function compared with a base line test. But when patients got the $1,500-per-dose placebo, their improvement was 9% greater than when they got the $100-per-dose placebo, the researchers reported. In another test, 67% of the patients were judged "very good" or having "marked improvement" after they took the expensive placebo, compared with 58% of patients after they took the purportedly cheap placebo.
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